TABLE 3

Summary of VigiBase total and fatal reports for cardioselective β1-blockers with asthma or bronchospasm as reported suspected adverse reactions from start to December 2019

Cardioselective β1-blockersReactions coded as asthmaReactions coded as bronchospasm
TotalOf which were fatalTotalOf which were fatal
Metoprolol28643226
Atenolol14113853
Bisoprolol9501081
Nebivolol290320
Betaxolol180860
Acebutolol51300
Celiprolol60411
Landiolol1000
Esmolol10111
Esatenolol1000