TABLE 2

Primary and secondary outcomes

Self-proningUsual careDifference between groups (95% CI)
Patients1017
O2 nasal flow L·min−1
 At baseline2.5 (2.0–3.0)2.0 (1·0–3·0)
 At 24 h1 (0.1–2.9)2.0 (0.5–3.0)−1 (−2.75–2)
SpO2/FiO2 ratio
 At baseline318 (284–341)336 (303–388)
 At 24 h390 (303–432)336 (294–422)54 (−91.6–133.0)
Respiratory rate breaths·min−1
 At baseline22.0 (20.0–25.8)20.0 (16.0–26.0)
 At 24 h20.0 (17.3–22.8)20.0 (18–24.0)0 (−6.5–3.5)
Heart rate beats·min−1
 At baseline83 (71–96)82 (75–89)
 At 24 h83 (72–89)80 (70–86)3 (−13–15)

Data are presented as n or median (interquartile range), unless otherwise stated. The difference between medians of the two randomised groups have been computed with their 95% confidence interval obtained by bootstrap using 1000 replications. O2: oxygen; SpO2: peripheral oxygen saturation; FiO2: inspiratory oxygen fraction.