Self-proning | Usual care | Difference between groups (95% CI) | |
Patients | 10 | 17 | |
O2 nasal flow L·min−1 | |||
At baseline | 2.5 (2.0–3.0) | 2.0 (1·0–3·0) | |
At 24 h | 1 (0.1–2.9) | 2.0 (0.5–3.0) | −1 (−2.75–2) |
SpO2/FiO2 ratio | |||
At baseline | 318 (284–341) | 336 (303–388) | |
At 24 h | 390 (303–432) | 336 (294–422) | 54 (−91.6–133.0) |
Respiratory rate breaths·min−1 | |||
At baseline | 22.0 (20.0–25.8) | 20.0 (16.0–26.0) | |
At 24 h | 20.0 (17.3–22.8) | 20.0 (18–24.0) | 0 (−6.5–3.5) |
Heart rate beats·min−1 | |||
At baseline | 83 (71–96) | 82 (75–89) | |
At 24 h | 83 (72–89) | 80 (70–86) | 3 (−13–15) |
Data are presented as n or median (interquartile range), unless otherwise stated. The difference between medians of the two randomised groups have been computed with their 95% confidence interval obtained by bootstrap using 1000 replications. O2: oxygen; SpO2: peripheral oxygen saturation; FiO2: inspiratory oxygen fraction.