Parameter | IPF | Non-IPF | p-value# |
Subjects n | 53 | 114 | |
Age years | 71 (68–76) | 68 (61–75) | 0.006 |
Female sex | 12 (23%) | 56 (49%) | 0.001 |
FVC % pred | 71 (61–82) | 68 (55–85) | 0.642 |
DLCO % pred | 46 (38–59) | 50 (39–63) | 0.214 |
Ever-smoker status | 29 (55%) | 60 (53%) | 0.674 |
UIP radiological pattern on CT | 47 (89%) | 25 (22%) | <0.0001 |
Reported symptom duration months | 24 (10–53) | 18 (8–42) | 0.215 |
6MWT distance m | 363 (297–385); (n=22) | 347 (268–469); (n=34) | 0.687 |
mMRC dyspnoea scale (0–4) | 2 (1–3) | 3 (1–3) | 0.147 |
PANAS Positive Score | 34 (28–37) | 33 (27–38) | 0.776 |
PANAS Negative Score | 12 (11–17) | 15 (12–20) | 0.043 |
PANAS ratio >2.9 | 23 (44%) | 30 (28%) | 0.042 |
SMAS-30 Taking Initiatives subscore (0–100) | 70 (60–84) | 68 (56–84) | 0.508 |
SMAS-30 Investment behaviour subscore (0–100) | 68 (56–78) | 64 (52–80) | 0.797 |
SMAS-30 Self-efficacy subscore (0–100) | 92 (84–100) | 92 (82–100) | 0.539 |
SMAS-30 Total (0–100) | 70 (59–80) | 68 (59–80) | 0.802 |
CRQ Dyspnoea | 5.8 (4.1–6.6) | 5.2 (3.4–6.2) | 0.165 |
CRQ Fatigue | 4.5 (3.5–5.3) | 4.0 (3.0–5.0) | 0.068 |
CRQ Emotional subscale | 5.3 (4.5–6.0) | 5.0 (4.1–5.9) | 0.104 |
CRQ Mastery | 5.5 (4.5–6.3) | 5.3 (4.0–6.3) | 0.179 |
CRQ Emotional Function (1–7) | 5 (4.5–6) | 5 (4.1–5.9) | 0.104 |
CRQ Physical score | 5.3 (3.9–5.7) | 4.7 (3.2–5.5) | 0.057 |
Data are presented as median (interquartile range) or n (%), unless otherwise stated. IPF: idiopathic pulmonary fibrosis; FVC: forced vital capacity; DLCO: diffusion capacity for carbon monoxide; UIP: usual interstitial pneumonia; CT: computed tomography; 6MWT: 6-min walk test; mMRC: modified Medical Research Council; PANAS: positive and negative affect survey; SMAS-30: self-management assessment survey 30. #: comparison between IPF and non-IPF subjects.