TABLE 1

Demographic and clinical characteristics at the year 25 study visit and spirometry at the year 30 study visit

EmphysemaNo emphysema
Subjects1722319
Age years50±3.550±3.6
Female77 (45)1350 (58)
Race
 Black115 (67)1031 (44)
 White57 (33)1288 (56)
Clinical centre
 Birmingham38 (22)550 (24)
 Chicago32 (19)518 (22)
 Minneapolis57 (33)569 (25)
 Oakland45 (26)682 (29)
Height cm171±9.1170±9.4
BMI kg·m−227±5.530±7.1
Education years13±2.415±2.6
Pack years at year 2520±154.0±8.4
Cigarettes per day among current and former smokers only8.2±9.31.2±4.1
Smoking status
 Never26 (15)1542 (66)
 Former36 (21)515 (22)
 Current110 (64)262 (11)
Spirometry
 FEV1 L2.45±0.792.74±0.75
 FEV1 % predicted82.6±20.392.8±15.5
 FVC L3.5±0.943.6±0.98
 FVC % predicted92.3±15.994.0±14.5
 FEV1/FVC ratio0.70±0.110.77±0.06

Data are presented as mean±sd or n (%), unless otherwise stated. BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.