Characteristics of sarcoidosis patients stratified by monocyte CD200R phenotype
CD200Rlow | CD200Rhigh | p-value | |
Patients | 14 | 11 | |
Scadding chest radiograph stage | 0.265 | ||
0 | 1 | 2 | |
1 | 4 | 1 | |
2 | 5 | 7 | |
4 | 4 | 1 | |
Angiotensin converting enzyme U·L−1 | 92 (52–136) | 104 (74–155) | 0.695 |
C-reactive protein mg·L−1 | 2.0 (1.4–5.5) | 2.8 (0.6–9.6) | 0.217 |
Age years# | 53.5 (40–73) | 50.0 (38–67) | 1.00 |
FEV1 % pred | 99 (69–110) | 92 (82–113) | 0.428 |
FVC % pred | 103 (76–115) | 90 (82–114) | 0.428 |
FEV1/FVC | 0.79 (0.75–0.84) | 0.83 (0.76–0.86) | 0.238 |
Time since diagnosis months | 20 (9–51) | 31 (10–73) | 0.695 |
Sex | 1.00 | ||
Male | 8 | 7 | |
Female | 6 | 4 | |
White blood cell count ×109 L−1 | 5.4 (4.15–6.20) | 4.3 (3.50–5.60) | 0.196 |
Lymphocyte count ×109 L−1 | 0.93 (0.74–1.41) | 0.74 (0.62–1.02) | 0.279 |
Monocyte count ×109 L−1 | 0.55 (0.44–0.72) | 0.42 (0.24–0.70) | 0.252 |
Neutrophil count ×109 L−1 | 3.42 (2.70–3.98) | 2.70 (2.33–3.97) | 0.336 |
Eosinophil count ×109 L−1 | 0.15 (0.13–0.23) | 0.20 (0.08–0.21) | 0.797 |
T-lymphocyte count ×109 L−1 | 0.61 (0.36–0.91) | 0.48 (0.33–0.63) | 0.403 |
CD4+ T-lymphocyte count ×109 L−1 | 0.36 (0.22–0.70) | 0.30 (0.16–0.45) | 0.596 |
CD8+ T-lymphocyte count ×109 L−1 | 0.20 (0.11–0.40) | 0.17 (0.09–0.21) | 0.290 |
B-lymphocyte count ×109 L−1 | 0.16 (0.07–0.21) | 0.14 (0.08–0.23) | 0.499 |
Natural killer cell count ×109 L−1 | 0.17 (0.12–0.22) | 0.15 (0.09–0.26) | 0.450 |
Data are presented as n or median (interquartile range), unless otherwise stated. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. #: median (range). Statistical comparisons by nonparametric independent samples median test or Pearson's Chi-squared test.