Parameter | PD-L1 expression ≥50% of tumour cells defined as positive | PD-L1 expression ≥1% of tumour cells defined as positive | ||

Estimate | 95% CI | Estimate | 95% CI | |

Sensitivity % | 100 | 46–100 | 86 | 56–97 |

Specificity % | 63 | 36–84 | 43 | 12–80 |

Positive predictive value % | 45 | 18–75 | 75 | 47–92 |

Negative predictive value % | 100 | 66–100 | 60 | 17–93 |

Positive likelihood ratio | 2.67 | 1.42–5.02 | 1.50 | 0.76–2.95 |

Negative likelihood ratio | 0.00 | Not defined | 0.33 | 0.07–1.56 |