Hypothyroidism | No hypothyroidism | p-value | |
Patients | 538 | 3284 | |
Multiorgan sarcoidosis ≥3 organs¶ | 276/532 (52) | 1444/3154 (46) | 0.009 |
Lungs | 377/492 (77) | 2201/2909 (76) | 0.64 |
Bones or vertebrae | 43/352 (12) | 234/2062 (11) | 0.64 |
Brain or cranial nerves | 51/351 (14.5) | 275/2077 (13) | 0.51 |
Peripheral nerves | 105/387 (27) | 518/2234 (23) | 0.09 |
Central lymph nodes+ | 282/431 (65) | 1431/2457 (58) | 0.005 |
Peripheral lymph nodes§ | 122/391 (31) | 623/2210 (28) | 0.23 |
Eyes | 138/405 (34) | 604/2318 (26) | 0.001 |
Cardiac | 59/384 (15) | 335/2196 (15) | 0.96 |
Joints | 141/408 (35) | 632/2314 (27) | 0.003 |
Kidneys | 33/350 (9) | 163/2047 (8) | 0.36 |
Parotid or lacrimal glands | 35/351 (10) | 130/1985 (6.5) | 0.02 |
Stomach/intestines | 34/360 (9) | 153/2080 (7) | 0.17 |
Liver | 72/367 (20) | 312/2125 (15) | 0.02 |
Spleen | 51/356 (14) | 287/2064 (14) | 0.83 |
Muscles | 39/355 (11) | 209/2079 (10) | 0.59 |
Sinuses | 45/363 (12) | 216/2149 (10) | 0.18 |
Skin | 167/412 (40.5) | 750/2308 (32.5) | 0.001 |
Newly arising comorbidities after sarcoid diagnosisƒ | |||
Probably sarcoid-related | 274/498 (55) | 1352/3284 (41) | <0.001 |
Probably steroid-related | 284/498 (57) | 1377/3284 (42) | <0.001 |
Data are presented as n or n/N total (%), unless otherwise stated. #: Patients were asked whether or not the organ involvement is a confirmed diagnosis, suspected or if they were unsure. Prevalence presented in this table is based on confirmed diagnosis only as reported by the patients. For this analysis, answers suspected or “not involved” were regarded as “not involved”. “Unsure” or missing were regarded as missing values. ¶: Multiorgan sarcoidosis defined if three or more organs were involved. +: Lymph nodes in the chest and abdomen. §: Axillary, cervical and inguinal lymph nodes. ƒ: Probably sarcoid-related: cancer, chronic fatigue syndrome, chronic pain syndrome, congestive heart failure, depression, fibromyalgia, lymphoma and sleep disorders; probably steroid-related: diabetes mellitus, cataracts, glaucoma, obesity, hypertension, osteoporosis/osteopenia and sleep apnoea.