Medical patients: univariate predictors of hospital mortality
| Variable | N | OR (95% CI) | p-value |
| Age years | 167 | 1.02 (1.01–1.04) | 0.005 |
| Female (ref.) | 167 | 0.914 (0.481–7.738) | 0.784 |
| PH group | 167 | 0.704 | |
| 1 Pulmonary arterial hypertension | Ref. | ||
| 2 PH due to left heart disease | 1.568 (0.303–8.120) | 0.592 | |
| 3 PH due to lung disease/hypoxia | 1.307 (0.376–4.541) | 0.674 | |
| 4 Chronic thromboembolic PH | 0.882 (0.359–2.169) | 0.785 | |
| 5 Unclear/multifactorial | 2.195 (0.656–7.350) | 0.202 | |
| Admission reason# | 167 | 0.03 | |
| Heart failure | Ref. | Ref. | |
| Respiratory failure/chest sepsis | 0.554 (0.254–1.208) | 0.138 | |
| Sepsis (other) | 0.356 (0.099–1.277) | 0.113 | |
| Pulmonary embolism | 0.800 (0.150–4.274) | 0.794 | |
| Arrhythmia | 0.133 (0.028–0.646) | 0.012 | |
| Renal failure | 0.267 (0.066–1.079) | 0.064 | |
| Other | 0.200 (0.051–0.779) | 0.020 | |
| ISWD | 102 | 0.998 (0.995–1.001) | 0.242 |
| APACHE II | 137 | 1.180 (1.095–1.270) | <0.001 |
| Heart rate | 166 | 1.011 (0.995–1.028) | 0.190 |
| mSAP mmHg | 163 | 0.983 (0.964–1.003) | 0.100 |
| Respiratory rate | 167 | 1.046 (1.005–1.087) | 0.026 |
| SpO2 % | 167 | 0.984 (0.939–1.030) | 0.482 |
| FiO2 | 165 | 5.896 (1.445–24.061) | 0.013 |
| PaO2 kPa | 142 | 0.959 (0.888–1.036) | 0.292 |
| SpO2/FiO2 ratio | 134 | 0.997 (0.993–1.001) | 0.114 |
| PaO2/FiO2 ratio | 134 | 0.983 (0.959–1.008) | 0.187 |
| Central venous pressure mmHg | 54 | 1.096 (1.021–1.177) | 0.011 |
| Glasgow Coma Scale | 138 | 0.727 (0.539–0.980) | 0.036 |
| pH | 148 | 0.007 (0.000–0.393) | 0.016 |
| Base excess mEq·L−1 | 147 | 0.933 (0.886–0.984) | 0.01 |
| Lactate mmol·L−1 | 141 | 1.425 (1.117–1.817) | 0.004 |
| Serum sodium mmol·L−1 | 157 | 0.937 (0.884–0.993) | 0.027 |
| Serum urea mmol·L−1 | 156 | 12.7 (4.37–80.2) | 0.001 |
| Serum creatinine µmol·L−1 | 155 | 1.005 (1.001–1.009) | 0.013 |
| Total bilirubin µmol·L−1 | 143 | 6.08 (2.97–19.8) | 0.022 |
| AST IU·L−1 | 123 | 0.999 (0.995–1.002) | 0.456 |
| CRP mg·L−1 | 141 | 1.005 (1.000–1.009) | 0.054 |
| Haemoglobin g·L−1 | 157 | 0.990 (0.978–1.003) | 0.123 |
| Platelets ×109·L−1 | 156 | 0.997 (0.994–1.000) | 0.033 |
| Right atrial pressure mmHg | 109 | 1.044 (0.990–1.101) | 0.108 |
| Mean PAP mmHg | 114 | 1.005 (0.973–1.037) | 0.775 |
| PAWP mmHg | 102 | 1.000 (0.919–1.088) | 1.000 |
| Cardiac output L·min−1 | 110 | 0.909 (0.743–1.112) | 0.352 |
| Cardiac index L·min−1·m−2 | 104 | 0.838 (0.584–1.201) | 0.335 |
| PVR dyn·s−1·cm−5 | 99 | 1.000 (0.999–1.001) | 0.482 |
| SvO2 % | 102 | 0.966 (0.929–1.005) | 0.087 |
Variables either at most recent review prior to admission (Right heart catheter data, ISWD at 2 weeks to 18 months prior to admission) or at critical care admission (e.g. laboratory tests and physiological observations). Bold indicates statistical significance. PH: pulmonary hypertension; ISWD: incremental shuttle walking distance; APACHE II: Acute Physiology and Chronic Health Evaluation II; mSAP: mean systemic arterial pressure; SpO2: oxygen saturation measured by pulse oximetry; FiO2: inspiratory oxygen fraction; PaO2: arterial oxygen tension; AST: aspartate aminotransferase; CRP: C-reactive protein; PAP: pulmonary artery pressure; PAWP: pulmonary arterial wedge pressure; PVR: pulmonary vascular resistance; SvO2: mixed venous oxygen saturation. #: main indication for critical care admission.