Baseline characteristics

Subjects n242
Age years52.5 (17–87)
PH diagnostic group
 1 Pulmonary arterial hypertension162 (66.9)
  Idiopathic/heritable/drugs and toxins96 (59.3)
  Connective tissue disease associated40 (24.7)
  Congenital heart disease associated18 (11.1)
  Others8 (4.9)
 2 PH due to left heart disease13 (5.3)
 3 PH due to lung disease/chronic hypoxia14 (5.8)
 4 Chronic thromboembolic PH39 (16.1)
 5 Unclear/multifactorial14 (5.8)
WHO functional class#
ISWD m#190 (0–1020)
Pulmonary haemodynamics
 mRAP mmHg10.0 (1–34)
 mPAP mmHg47 (14–74)
 PAWP mmHg10 (0–33)
 CO L·min−14.7 (1.87–14.2)
 CI L·min−1·m−22.6 (1.2–6.0)
 PVR dyn·s−1·cm−5561 (84–2400)
SvO2 %65 (35–86)

Data are presented as median (min–max), % or n (%), unless otherwise stated. PH: pulmonary hypertension; WHO: World Health Organization; ISWD: incremental shuttle walk distance; mRAP: mean right atrial pressure; mPAP: mean pulmonary artery pressure; PAWP: pulmonary arterial wedge pressure; CO: cardiac output; CI: cardiac index; PVR pulmonary vascular resistance; SvO2: mixed venous oxygen saturations. #: 2 weeks to 18 months prior to admission; : nearest prior to admission.