Dog dander-sensitised cases | Healthy controls | p-value | |
Subjects | 49 | 17 | |
Female | 17 (35) | 9 (53) | 0.19 |
Age years mean (range) | 13.2 (10–17) | 13.3 (10–17) | 0.88 |
Exposure to dogs | |||
Dog at home | 12 (24) | 0 (0) | 0.03 |
Dog in the catchment area | 39 (80) | 11 (65) | 0.32 |
Lung function | |||
FEV1 % pred | 102 (93–109) | 110 (99–119) | 0.02 |
Reversibility % | 5.7 (1.8–11.5) | 3.7 (1.6–5.9) | 0.12 |
FeNO ppb | 32 (20–59) | 15 (11–18) | <0.001 |
Asthma control test# | 22 (19–24) | 25 (25–27) | <0.001 |
White blood cell count# | |||
Leukocytes ×109 cells·L−1 | 5.9 (5.1–7.5) | 6.8 (6.0–7.6) | 0.28 |
Neutrophils ×109 cells·L−1 | 2.9 (2.3–4.1) | 3.2 (2.9–4.8) | 0.13 |
Eosinophils ×109 cells·L−1 | 0.3 (0.25–0.6) | 0.2 (0.1–0.2) | 0.001 |
Data are presented as n, n (%) or median (interquartile range), unless otherwise stated. Bold type represents statistical significance. FEV1: forced expiratory volume in 1 s; FeNO: exhaled nitric oxide fraction. #: dog dander-sensitised cases n=48.