TABLE 1

Demographic and clinical characteristics of dog dander sensitised children and healthy controls

Dog dander-sensitised casesHealthy controlsp-value
Subjects4917
Female17 (35)9 (53)0.19
Age years mean (range)13.2 (10–17)13.3 (10–17)0.88
Exposure to dogs
 Dog at home12 (24)0 (0)0.03
 Dog in the catchment area39 (80)11 (65)0.32
Lung function
 FEV1 % pred102 (93–109)110 (99–119)0.02
 Reversibility %5.7 (1.8–11.5)3.7 (1.6–5.9)0.12
FeNO ppb32 (20–59)15 (11–18)<0.001
 Asthma control test#22 (19–24)25 (25–27)<0.001
White blood cell count#
 Leukocytes ×109 cells·L−15.9 (5.1–7.5)6.8 (6.0–7.6)0.28
 Neutrophils ×109 cells·L−12.9 (2.3–4.1)3.2 (2.9–4.8)0.13
 Eosinophils ×109 cells·L−10.3 (0.25–0.6)0.2 (0.1–0.2)0.001

Data are presented as n, n (%) or median (interquartile range), unless otherwise stated. Bold type represents statistical significance. FEV1: forced expiratory volume in 1 s; FeNO: exhaled nitric oxide fraction. #: dog dander-sensitised cases n=48.