iPAH | Pc-PH | |
Patients | 719 | 112 |
Age years | 66 (51–75) | 70.5 (64–79) |
Female sex | 386 (54) | 72 (64) ns |
Body surface area m2 | 1.77 (1.63–1.94) | 1.92 (1.79–2.06) |
Cardiac output L·min−1 | 4.18 (3.38–5.00) | 5.49 (4.33–6.29) |
Cardiac index L·min−1·m−2 | 2.35 (2.90–2.79) | 2.77 (2.29–3.35) |
Heart rate beats·min−1 | 79 (68–88) | 78 (63–88) ns |
Stroke volume mL | 54 (42–69) | 70 (55–93) |
Stroke volume index mL·m−2 | 30 (24–38) | 37 (29–48) |
mPAP mmHg | 46 (39–54) | 38 (33–48) |
Pulmonary arterial pulse pressure mmHg | 45 (36–53) | 36 (26–43) |
PAWP mmHg | 9 (6–11) | 21 (17–25) |
TPG mmHg | 38 (31–46) | 18 (12–25) |
RAP mmHg | 7 (4–11) | 13 (10–18) |
PVR WU | 9.1 (6.6–12.5) | 3.3 (2.4–4.7) NA |
PAC mL·mmHg−1 | 1.20 (0.88–1.68) | 2.18 (1.46–3.07) |
RC-time ms | 650 (546–767) | 396 (321–489) |
Data are presented as n, median (interquartile range) or n (%). mPAP: mean pulmonary artery pressure; PAC: total pulmonary arterial compliance; PAH: pulmonary arterial hypertension; PAWP: pulmonary artery wedge pressure; PVR: pulmonary vascular resistance; RAP: right atrial pressure; RC-time: the PVR times SV/PP product; TPG: transpulmonary pressure gradient (mPAP–PAWP); WU: Wood units. Each p<0.05 except where indicated ns (not significant) or NA (not applicable).