TABLE 2

Case–control comparison over the 2 years following Achromobacter xylosoxidans initial infection

	Cases	Controls	p-value^#
Subjects	45	45
FEV₁ % pred	78.4±16	93.2±17	0.003*
BMI z-score	−0.1±1	−0.01±0.8	0.7
Annual rate of respiratory exacerbations	4.7±2.3	1.9±1.1	0.0001*
Annual rate of hospitalisations	0.5±0.7	0	0.0001*
Annual rate of oral antibiotic courses	5.3±2.4	2.2±1.4	0.0001*
Annual rate of intravenous antibiotic courses	1.3±1.6	0.2±0.5	0.0001*
Pseudomonas aeruginosa colonisation	51 (23)	29 (13)	0.04*
MRSA colonisation	16 (7)	2 (1)	0.05*

Data are presented as mean±sd or % (n) over the 2 years following A. xylosoxidans initial infection for the cases (between T0 and T+24). FEV₁: forced expiratory volume in 1 s; BMI: body mass index; MRSA: methicillin-resistant Staphylococcus aureus. ^#: for the comparison of sex, age, CFTR genotypes and pancreatic status matched cases and controls. *: p<0.05.