TABLE 1

Included variables from the “risk table” in the 2015 European Society of Cardiology (ESC)/European Respiratory Society (ERS) guidelines for the diagnosis and treatment of pulmonary hypertension and their cut-off values

Determinants of prognosisLow riskIntermediate riskHigh risk
WHO functional classI, IIIIIIV
6MWD m>440165–440<165
NT-proBNP levels ng·L−1<300300–1400>1400
Imaging (echocardiography)RA area <18 cm2RA area 18–26 cm2RA area >26 cm2
No pericardial effusionPericardial effusion
Haemodynamics
 RAP mmHg<88–14>14
 CI L·min−1·m−2≥2.52.0–2.4<2.0
SvO2 %>6560–65<60

Adopted from the “risk table” in the 2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension [6]. WHO: World Health Organization; 6MWD: 6-min walk distance; NT-proBNP: N-terminal pro-hormone of brain natriuretic peptide; RA: right atrium; RAP: right atrial pressure; CI: cardiac index; SvO2: mixed venous oxygen saturation.