TABLE 1

Case–control comparison over the 2 years prior to Achromobacter xylosoxidans initial infection

	Cases	Controls	p-value^#
Subjects	45	45
FEV₁ % pred	88.0±18	92.7±17	0.3
BMI z-score	0.03±0.9	−0.03±0.9	0.8
Annual rate of respiratory exacerbations	2.8±1.7	2.0±1.3	0.02*
Annual rate of hospitalisations	0.1±0.4	0	0.05*
Annual rate of oral antibiotic courses	3.7±1.8	2.4±1.6	0.001*
Annual rate of intravenous antibiotic courses	0.4±0.9	0.12±0.4	0.03*
Pseudomonas aeruginosa colonisation	64 (29)	24 (11)	0.0002*
MRSA colonisation	9 (4)	9 (4)	0.9

Data are presented as mean±sd or % (n) over the 2 years prior to A. xylosoxidans initial infection for the cases (between T−24 and T0). FEV₁: forced expiratory volume in 1 s; BMI: body mass index; MRSA: methicillin-resistant Staphylococcus aureus. ^#: for the comparison of sex, age, CFTR genotypes and pancreatic status matched cases and controls. *: p<0.05.