Differential diagnostic characteristics of type 2 (T2)-low versus T2-high asthma
| T2-low asthma | T2-high asthma | |
| Onset | Late | Early |
| Symptoms | Mostly significant | May be significant |
| Obesity | Often present | May be present |
| Smoking | Often present | May be present |
| Response to inhaled corticosteroids | Often poor | Usually good |
| Severity of asthma | Often difficult to treat | Mild to severe |
| Asthma control | Often poor | Variable |
| Sputum eosinophils | Absent | Normal or high levels |
| Sputum neutrophils | Frequently present | May be present |
| Exhaled nitric oxide | Usually normal | Elevated or normal |
| Airways | Often present | May be present |