Demographic data for preterm infants and correlation to airway epithelial cell wound repair at 72 h
| Preterm | Correlation# to % repair at 72 h | p-value | |
| Participants n | 22 | ||
| Male n | 17 | −0.019 | 0.932 |
| Gestation, weeks | 28.3 (26.2–30.5), 24–31.7 | 0.035 | 0.877 |
| Bronchopulmonary dysplasia | 8 (36) | 0.162 | 0.470 |
| Birthweight z-score | −0.02 (−0.8–0.45), −1.89–1.79 | 0.091 | 0.687 |
| Age at brushing, days | 508±38.6 (447–583) | −0.262 | 0.239 |
| Total hours of supplemental oxygen required | 198 (16.5–1279.5), 1–3381 | 0.164 | 0.446 |
| Total hours of respiratory support (any) | 1223 (548.5–1920), 54–3082 | 0.054 | 0.813 |
| Total hours mechanical ventilation | 11.5 (0.0–73.5), 0–1112 | 0.007 | 0.974 |
| Total hours CPAP | 777 (225–1134), 54–1658 | −0.011 | 0.962 |
| Total hours HHF | 314.5 (0.0–719.75), 0.0–1124 | −0.021 | 0.928 |
| Administered surfactant | 14 (64) | 0.024 | 0.915 |
| Received antenatal steroids >24 h prior to delivery | 14 (64) | −0.442 | 0.040* |
| Received postnatal steroids | 2 (9) | −0.207 | 0.355 |
| Chorioamnionitis | 9 (41) | −0.205 | 0.360 |
| Wheeze in first year of life | 13 (59) | −0.177 | 0.432 |
| Respiratory hospitalisation in first year of life | 9 (41) | −0.205 | 0.360 |
| Atopic¶ | 4 (18) | −0.201 | 0.383 |
| Tobacco smoke exposure | 6 (27) | 0.049 | 0.827 |
| Shift+ at 36 weeks, kPa | 11.15 (9.6–12.5), 7.6–24.9 | −0.101 | 0.662 |
| Shift+ at 1 year, kPa | 6.70 (6.2–7.1), 5.5–8.9 | −0.062 | 0.799 |
Data are presented as median (interquartile range) with range, n (%) or mean±sd (range), unless otherwise stated. CPAP: continuous positive airway pressure; HHF: humidified high flow. #: calculated using either Spearman's Rho correlation or point-biserial correlation as appropriate; ¶: defined as the presence of hayfever or eczema in the first year of life; +: shift refers to the magnitude by which the oxygen-haemoglobin dissociation curve has moved along the x-axis. *: p<0.05.