Demographic data for preterm infants and correlation to airway epithelial cell wound repair at 72 h

PretermCorrelation# to % repair at 72 hp-value
Participants n22
Male n17−0.0190.932
Gestation, weeks28.3 (26.2–30.5), 24–31.70.0350.877
Bronchopulmonary dysplasia8 (36)0.1620.470
Birthweight z-score−0.02 (−0.8–0.45), −1.89–1.790.0910.687
Age at brushing, days508±38.6 (447–583)−0.2620.239
Total hours of supplemental oxygen required198 (16.5–1279.5), 1–33810.1640.446
Total hours of respiratory support (any)1223 (548.5–1920), 54–30820.0540.813
 Total hours mechanical ventilation11.5 (0.0–73.5), 0–11120.0070.974
 Total hours CPAP777 (225–1134), 54–1658−0.0110.962
 Total hours HHF314.5 (0.0–719.75), 0.0–1124−0.0210.928
Administered surfactant14 (64)0.0240.915
Received antenatal steroids >24 h prior to delivery14 (64)−0.4420.040*
Received postnatal steroids2 (9)−0.2070.355
Chorioamnionitis9 (41)−0.2050.360
Wheeze in first year of life13 (59)−0.1770.432
Respiratory hospitalisation in first year of life9 (41)−0.2050.360
Atopic4 (18)−0.2010.383
Tobacco smoke exposure6 (27)0.0490.827
Shift+ at 36 weeks, kPa11.15 (9.6–12.5), 7.6–24.9−0.1010.662
Shift+ at 1 year, kPa6.70 (6.2–7.1), 5.5–8.9−0.0620.799

Data are presented as median (interquartile range) with range, n (%) or mean±sd (range), unless otherwise stated. CPAP: continuous positive airway pressure; HHF: humidified high flow. #: calculated using either Spearman's Rho correlation or point-biserial correlation as appropriate; : defined as the presence of hayfever or eczema in the first year of life; +: shift refers to the magnitude by which the oxygen-haemoglobin dissociation curve has moved along the x-axis. *: p<0.05.