TABLE 3

Incidence rate (n per 1000 person-years) of different asthma variables by age group and sex and by use of different definitions of population at risk

OutcomeCohort followed from 1996 to 2006p-value#Cohort followed from 2006 to 2016p-value#
Age yearsSexAge yearsSex
20–3940–5960–69FMAll20–3940–5960–69FMAll
Model APhysician-diagnosed asthma2.62.42.62.72.22.40.2852.82.62.53.51.72.60.001
Asthma medication use4.43.93.34.73.44.00.0284.84.73.95.73.34.50.001
Recurrent wheeze4.94.65.54.55.14.80.3964.55.94.95.35.25.30.874
Model BPhysician-diagnosed asthma4.44.54.15.23.64.40.0084.84.45.55.83.64.80.001
Asthma medication use7.67.46.39,05.67.3<0.0018.58.08.610.26.28.3<0.001
Recurrent wheeze8.28.910.58.79.18.90.6318.19.08.38.58.78.60.848
Model CAsthma medication use6.25.75.27,04.65.8<0.0016.66.85.98.34.76.5<0.001
Recurrent wheeze6.06.37.96.36.66.50.6987.87.16.27.46.87.10.473

Model A: excluded from population at risk were those who at baseline reported any of physician-diagnosed asthma, ever-asthma, current use of asthma medicine and recurrent wheeze. Model B: excluded from population at risk were those who reported physician-diagnosed asthma at baseline. Model C: excluded from population at risk were those who at baseline reported the outcome variable. F: females; M: males. #: p-value for differences in cumulative incidence by sex, p-values in bold indicate statistical significance; : no statistical difference by study period of any of the outcome variables was found.