Characteristics | Discharged from hospital | Deceased in hospital | p-value |
Patients | 1365 | 470 | |
Age years | 65 (54–75) | 73 (65–83) | <2.2×10−16# |
Male sex | 805 (59.0) | 262 (55.7) | 0.242 |
Race/ethnicity | 0.374 | ||
White | 275 (20.1) | 111 (23.6) | |
Black | 277 (20.3) | 83 (17.7) | |
Hispanic | 404 (29.6) | 138 (29.4) | |
Other | 236 (17.3) | 73 (15.5) | |
Missing | 173 (12.7) | 65 (13.8) | |
Smoking status | 0.714 | ||
Never smoker | 688 (50.4) | 229 (48.7) | |
Ever smoker | 384 (28.1) | 132 (28.1) | |
Missing | 293 (21.5) | 109 (23.2) | |
Baseline comorbidities (details in Table S1) | 1.4×10−08# | ||
0 | 456 (33.4) | 89 (18.9) | |
1–2 | 534 (39.1) | 196 (41.7) | |
>2 | 375 (27.5) | 185 (39.4) | |
BMI kg·m−2 | 27.55 (23.88–32.12) | 27.46 (24.32–32.48) | 0.331 |
Admission vital signs | |||
Systolic blood pressure maximum mmHg | 143 (129–159) | 144 (129–161) | 0.531 |
Diastolic blood pressure maximum mmHg | 83 (76–92) | 81 (73–91) | 0.017 |
Heart rate maximum beats·min−1 | 101.00 (90.75–114.00) | 103.00 (91.00–120.75) | 0.009 |
Respiratory rate maximum breaths·min−1 | 22 (20–28) | 24 (20–30) | 9.7×10−06# |
Temperature maximum °F | 99.8 (98.6–101.3) | 99.6 (98.6–101.1) | 0.064 |
Temperature maximum °C | 37.7 (37.0–38.5) | 37.6 (37.0–38.4) | |
Oxygen saturation minimum % | 93 (90–95) | 90 (84–94) | 3.4×10−16# |
Baseline laboratory tests | |||
White blood cell ×103cells·μL−1 | 7.60 (5.50–10.40) | 8.14 (5.90–12.28) | 0.011 |
Lymphocyte % | 13.05 (8.30–18.58) | 11.00 (7.25–16.95) | 0.003 |
Neutrophil % | 78.60 (70.45–84.77) | 81.90 (73.40–87.10) | 2.8×10−05# |
Haemoglobin g·dL−1 | 12.70 (11.10–13.90) | 12.90 (11.10–14.10) | 0.448 |
Platelet ×103 platelets·μL−1 | 221.00 (167.00–293.00) | 187.00 (147.00–244.00) | 1.7×10−09# |
Serum creatinine mg·dL−1 | 0.95 (0.73–1.41) | 1.20 (0.82–2.00) | 1.2×10−4# |
Estimated glomerular filtration rate mL·min−1·1.73 m−2 | 54.00 (30.15–77.00) | 41.28 (26.00–58.33) | 7.3×10−11# |
Alanine aminotransferase U·L−1 | 30.00 (19.00–50.00) | 30.00 (20.25–50.75) | 0.885 |
Aspartate aminotransferase U·L−1 | 40.00 (27.00–63.50) | 48.00 (33.00–71.75) | 1.7×10−4# |
Total bilirubin mg·dL−1 | 0.60 (0.40–0.80) | 0.50 (0.40–0.80) | 0.356 |
C-reactive protein mg·L−1 | 113.50 (53.70–194.30) | 159.10 (90.82–235.70) | 1.0×10−09# |
Ferritin ng·mL−1 | 697.00 (330.00–1512.00) | 1038.00 (480.00–2092.00) | 8.9×10−05# |
Lactate dehydrogenase U·L−1 | 412.00 (312.00–528.50) | 516.50 (381.25–660.75) | <2.2×10−16# |
Baseline D-dimer μg·mL−1 | 1.37 (0.79–2.46) | 1.76 (1.08–2.92) | 1.6×10−05# |
Days from admission to start of anticoagulation | 0.55 (0.20–1.68) | 0.67 (0.24–2.13) | 0.017 |
Data are presented as n, n (%) or median (interquartile range), unless otherwise stated. #: Significant after multiple testing.
BMI: Body mass index.