TABLE 1

Characteristics of hospitalised COVID-19 patients according to survival status

CharacteristicsDischarged from hospitalDeceased in hospitalp-value
Patients1365470
Age years65 (54–75)73 (65–83)<2.2×10−16#
Male sex805 (59.0)262 (55.7)0.242
Race/ethnicity0.374
 White275 (20.1)111 (23.6)
 Black277 (20.3)83 (17.7)
 Hispanic404 (29.6)138 (29.4)
 Other236 (17.3)73 (15.5)
 Missing173 (12.7)65 (13.8)
Smoking status0.714
 Never smoker688 (50.4)229 (48.7)
 Ever smoker384 (28.1)132 (28.1)
 Missing293 (21.5)109 (23.2)
Baseline comorbidities (details in Table S1)1.4×10−08#
 0456 (33.4)89 (18.9)
 1–2534 (39.1)196 (41.7)
 >2375 (27.5)185 (39.4)
BMI kg·m−227.55 (23.88–32.12)27.46 (24.32–32.48)0.331
Admission vital signs
 Systolic blood pressure maximum mmHg143 (129–159)144 (129–161)0.531
 Diastolic blood pressure maximum mmHg83 (76–92)81 (73–91)0.017
 Heart rate maximum beats·min−1101.00 (90.75–114.00)103.00 (91.00–120.75)0.009
 Respiratory rate maximum breaths·min−122 (20–28)24 (20–30)9.7×10−06#
 Temperature maximum °F99.8 (98.6–101.3)99.6 (98.6–101.1)0.064
 Temperature maximum °C37.7 (37.0–38.5)37.6 (37.0–38.4)
 Oxygen saturation minimum %93 (90–95)90 (84–94)3.4×10−16#
Baseline laboratory tests
 White blood cell ×103cells·μL−17.60 (5.50–10.40)8.14 (5.90–12.28)0.011
  Lymphocyte %13.05 (8.30–18.58)11.00 (7.25–16.95)0.003
  Neutrophil %78.60 (70.45–84.77)81.90 (73.40–87.10)2.8×10−05#
 Haemoglobin g·dL−112.70 (11.10–13.90)12.90 (11.10–14.10)0.448
 Platelet ×103 platelets·μL−1221.00 (167.00–293.00)187.00 (147.00–244.00)1.7×10−09#
 Serum creatinine mg·dL−10.95 (0.73–1.41)1.20 (0.82–2.00)1.2×10−4#
 Estimated glomerular filtration rate mL·min−1·1.73 m−254.00 (30.15–77.00)41.28 (26.00–58.33)7.3×10−11#
 Alanine aminotransferase U·L−130.00 (19.00–50.00)30.00 (20.25–50.75)0.885
 Aspartate aminotransferase U·L−140.00 (27.00–63.50)48.00 (33.00–71.75)1.7×10−4#
 Total bilirubin mg·dL−10.60 (0.40–0.80)0.50 (0.40–0.80)0.356
 C-reactive protein mg·L−1113.50 (53.70–194.30)159.10 (90.82–235.70)1.0×10−09#
 Ferritin ng·mL−1697.00 (330.00–1512.00)1038.00 (480.00–2092.00)8.9×10−05#
 Lactate dehydrogenase U·L−1412.00 (312.00–528.50)516.50 (381.25–660.75)<2.2×10−16#
 Baseline D-dimer μg·mL−11.37 (0.79–2.46)1.76 (1.08–2.92)1.6×10−05#
Days from admission to start of anticoagulation0.55 (0.20–1.68)0.67 (0.24–2.13)0.017

Data are presented as n, n (%) or median (interquartile range), unless otherwise stated. #: Significant after multiple testing.

BMI: Body mass index.