Hazard ratios (HR) for the association between respiratory medication and a subsequent asthma exacerbation stratified by exacerbation status in the previous year
| Severe exacerbation last year# | No severe exacerbation last year¶ | |||
| n (%) | HR age + sex adjusted (95% CI, p-value) | n (%) | HR age + sex adjusted (95% CI, p-value) | |
| R03 medication | ||||
| None | 5 (6.8) | 160 (38.0) | ||
| Rescue | 5 (6.8) | 4.78 (1.10–20.82, p=0.037) | 30 (7.1) | 2.06 (0.96–4.44, p=0.065) |
| Controller | 20 (27.0) | 1.04 (0.30–3.65, p=0.953) | 147 (34.9) | 2.27 (1.41–3.67, p=0.001) |
| Controller and rescue | 44 (59.5) | 1.09 (0.33–3.56, p=0.889) | 84 (20.0) | 3.64 (2.16–6.16, p<0.001) |
| Controller to total ratio | ||||
| Controller/controller+rescue | 74 (100) | 0.26 (0.09–0.76, p=0.014) | 421 (100) | 1.13 (0.61–2.10, p=0.691) |
#: n=74; ¶: n=421. Bold indicates statistical significance.