TLC <LLN | DLCO <LLN | FEV1/FVC <LLN | RV >ULN | p-value | |
Subjects n | 25 | 18 | 11 | 10 | |
% of discharged subjects | 19 | 13 | 8 | 7 | |
Age, years | 62±10 | 59±12 | 68±5 | 64±6 | ns |
Males/females n/n | 20/5 | 10/8 | 8/3 | 5/4 | ns |
BMI, kg·m−2 | 28±5 | 27±4 | 28±5 | 28±4 | ns |
Current smokers n | 1 | 0 | 1 | 0 | |
Former smokers n | 2 | 1 | 3 | 2 | |
COPD n | 0 | 0 | 4 | 0 | |
Asthma n | 0 | 0 | 1 | 0 | |
CPAP n/total | 8/29 | 2/29 | 3/29 | 1/29 | ns |
MV n/total | 6/20 | 0/20 | 2/20 | 1/20 | ns |
mMRC dyspnoea, score | 1.84±0.80 | 1.22±0.55 | 1.27±0.90 | 1.3±0.67 | ns |
TLC, L | 4.54±1.05 | 5.36±1.04 | 6.07±1.22 | 6.89±1.60 | |
TLC, % | 69±9 | 90±10 | 106±13 | 114±12 | |
RV, L | 1.45±0.48 | 1.99±0.67 | 3.28±0.86 | 3.44±0.62 | |
RV, % predicted | 63±21 | 92±22 | 138±24 | 155±18 | |
RV/TLC | 0.33±0.10#,¶ | 0.37±0.09§,+ | 0.52±0.09#,§ | 0.51±0.99¶,+ | 0.01 |
RV/TLC, % predicted | 82±28#,¶ | 96±21§,+ | 125±21#,§ | 130±20¶,+ | 0.01 |
FVC, L | 3.11±0.85 | 3.36±0.71 | 2.92±0.81 | 3.40±1.25 | ns |
FVC, % predicted | 76±14§ | 89±14§ | 85±19 | 90±19 | 0.04 |
FEV1, L | 2.69±0.67 | 2.73±0.56 | 1.93±0.53 | 2.83±0.97 | ns |
FEV1, % predicted | 85±13 | 92±12 | 72±17 | 97±19 | ns |
FEV1/VC | 0.85±0.04 | 0.81±0.05 | 0.67±0.06 | 0.84±0.06 | |
FEV1/VC, % predicted | 109±6 | 102±6 | 83±5 | 107±7 | |
DLCO, mmol·kPa−1·min−1 | 6.16±1.97 | 5.36±1.09 | 5.67±2.02 | 6.95±2.19 | ns |
DLCO, % predicted | 68±19 | 63±10 | 73±28 | 82±17 | ns |
KCO, mmol·kPa−1·min−1·L−1 | 1.34±0.26 | 1.19±0.27 | 1.19±0.34 | 1.38±0.11§ | ns |
KCO, % predicted | 97±21§ | 80±13§ | 85±28 | 98±10 | 0.04 |
Data are presented as mean±sd, unless otherwise stated. TLC: total lung capacity; LLN: lower limit of normality; DLCO: diffusing capacity of the lung for carbon monoxide; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; RV: residual volume; ULN: upper limit of normality; BMI: body mass index; CPAP: continuous positive airway pressure; MV: mechanical ventilation; mMRC: modified Medical Research Council dyspnoea scale (at 6 months); VC: vital capacity; KCO: transfer coefficient of the lung for carbon monoxide (DLCO corrected for alveolar volume); ns: nonsignificant. #,¶,+,§: within each row, identical superscripts indicate significant difference.