Change in asthma control parameters between baseline, follow-up 1 and follow-up 2

Baseline (n=35)Follow-up 1 (n=35)Follow-up 2 (n=35)p-value: comparison baseline versus follow-up 1p-value: comparison follow-up 1 versus follow-up 2
FEV1, % pred82.2±21.892.5±16.195.8±16.2<0.0010.087
BDR, %20.3±22.8#8.7±10.4#7.2±9.3<0.0010.445
FeNO, ppb55 (26–87)21 (13–61)22.5 (11–40)+0.0020.724
mPAQLQ3.5 (3–4.7)5.5 (4.3–6.4)5.9 (4.3–6.8)0.0010.006
Exacerbations, n2 (0–8)1 (0–4)#0 (0–4)0.0330.001
AdherenceNot assessed78 (54–92)83 (56–93)0.302

Data are presented as mean±sd or median (interquartile range), unless otherwise stated. According to the data distribution, Wilcoxon signed rank or paired t-test were used. FEV1: forced expiratory volume in 1 s; BDR: bronchodilator reversibility; FeNO: exhaled nitric oxide fraction; mPAQLQ: median paediatric quality of life questionnaire score; ACT: Asthma Control Test. #: missing data for one child; : missing data for two children; +: missing data for five children.