Change in asthma control parameters between baseline, follow-up 1 and follow-up 2
| Baseline (n=35) | Follow-up 1 (n=35) | Follow-up 2 (n=35) | p-value: comparison baseline versus follow-up 1 | p-value: comparison follow-up 1 versus follow-up 2 | |
| FEV1, % pred | 82.2±21.8 | 92.5±16.1 | 95.8±16.2 | <0.001 | 0.087 |
| BDR, % | 20.3±22.8# | 8.7±10.4# | 7.2±9.3¶ | <0.001 | 0.445 |
| FeNO, ppb | 55 (26–87)¶ | 21 (13–61)¶ | 22.5 (11–40)+ | 0.002 | 0.724 |
| mPAQLQ | 3.5 (3–4.7) | 5.5 (4.3–6.4) | 5.9 (4.3–6.8)¶ | 0.001 | 0.006 |
| Exacerbations, n | 2 (0–8) | 1 (0–4)# | 0 (0–4) | 0.033 | 0.001 |
| Adherence | Not assessed | 78 (54–92) | 83 (56–93) | 0.302 | |
| ACT | 12.6±6.1# | 16.2±6.1# | 19.1±5.8¶ | 0.001 | 0.005 |
Data are presented as mean±sd or median (interquartile range), unless otherwise stated. According to the data distribution, Wilcoxon signed rank or paired t-test were used. FEV1: forced expiratory volume in 1 s; BDR: bronchodilator reversibility; FeNO: exhaled nitric oxide fraction; mPAQLQ: median paediatric quality of life questionnaire score; ACT: Asthma Control Test. #: missing data for one child; ¶: missing data for two children; +: missing data for five children.