High upper airway symptoms | Low upper airway symptoms | Odds ratio (95% CI) | p-value | |
Subjects n | 74 | 106 | ||
C-reactive protein mg·L−1 | 2.9 (1.8–4.8) | 2.9 (1.9–6.4) | 0.330 | |
Blood eosinophils (n=180) | ||||
% of total leukocytes | 3.0 (1.6–4.1) | 2.3 (1.4–3.1) | <0.05 | |
actual number, 109·L−1 | 0.20 (0.11–0.33) | 0.20 (0.10–0.21) | <0.05 | |
n (%) patients with ≥0.30×109·L−1 | 30 (41) | 19 (18) | 3.1 (1.6–6.2) | <0.001 |
n (%) patients with ≥3% | 36 (49) | 30 (29) | 2.4 (1.3–4.5) | <0.01 |
Sputum (n=87) | ||||
Eosinophils, % of total | 1.8 (0.3–6.3) | 0.5 (0–1.7) | <0.05 | |
n (%) patients with ≥3% | 12 (40) | 11 (21) | 2.5 (0.9–6.7) | 0.067 |
Neutrophils, % of total | 57±26% | 63±31 | 0.314 | |
Macrophages, % of total | 29 (15–49) | 21 (5–45) | 0.221 | |
Lymphocytes, % of total | 0.13 (0–0.59) | 0 (0–0.19) | <0.05 |
Data presented as the median and interquartile range, mean±sd, or count and percentage. Between-group comparisons calculated with either Mann–Whitney U test or t-test for continuous data or Chi-square test for categorical data. Odds ratios are unadjusted.