Univariate | Multivariate | ||
p-value | HR (CI) | p-value | |
Age | 0.001 | 1.04 (1.02–1.07) | 0.001 |
Gender, female | 0.077 | 0.77 (0.47–1.27) | 0.308 |
Diabetes mellitus | 0.759 | ||
Atrial fibrillation | 0.675 | ||
Ischaemic heart disease | 0.608 | ||
Ischaemic stroke | 0.546 | ||
Systemic hypertension | 0.858 | ||
Risk group at baseline# | <0.001 | 0.42 (0.25–0.70) | 0.001 |
Obesity | 0.199 | ||
Kidney dysfunction | 0.613 | ||
PAH type¶ | 0.145 | 1.98 (1.12–3.53) | 0.020 |
PAH: pulmonary arterial hypertension; CTD-PAH: connective tissue disease-associated pulmonary arterial hypertension; ILD: interstitial lung disease. Bold type highlights variables included in the multivariate model (p<0.15 in the univariate analysis). #Intermediate versus high risk. ¶CTD-PAH with ILD versus IPAH.