TABLE 1

Baseline characteristics

PlaceboTriamcinolonep-value
Subjects, n1615
Sex male, n (%)9 (56)9 (60)1.000
Age years#65 (55–74)63 (51–67)0.452
Adult-onset (>18 years) asthma, n (%)11 (69)8 (53)0.473
Atopic, n (%)7 (44)5 (33)0.716
BMI kg m−225.2±2.326.8±2.80.080
Pack-years#0 (0–1.5)0 (0–5)0.830
Fluticasone equivalent mg#500 (500–1000)500 (500–1000)0.578
OCS dependent, n (%)3 (19)2 (13)1.000
Exacerbations, preceding year#2 (0–3)2 (1–5)0.493
Blood eosinophils ×109 L−1#0.2 (0.1–0.4)0.2 (0.1–0.3)0.951
FENO ppb#35 (22–92)21 (13–26)0.036
Pb FEV1, % pred66±1677±170.235
Pb FEV1/FVC, % pred65±1272±80.060
FRC/TLC, % pred119±14111±150.097
ACQ total score#1.5 (1.0–2.4)1.3 (0.8–2.8)0.874
  • ​​​​​​​BMI: body mass index; OCS: oral corticosteroids; FENO: exhaled nitric oxide fraction; Pb: post-bronchodilator; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; FRC: functional residual capacity; TLC: total lung capacity; ACQ: asthma control questionnaire; IQR: interquartile range. #: median (IQR); : mean±sd.