Sex, history of pulmonary embolism and haemodynamics by patient disposition to intervention, all regions (n=1010)
| PEA operable candidates | BPA candidates not PEA operable | Neither PEA nor BPA | p-value (exploratory) | |
| Subjects n | 669 | 193 | 148 | |
| Age at diagnosis years | 61.0 (49.0–71.0) | 65.0 (52.0–74.0) | 70.0 (57.0–77.0) | <0.001 |
| Sex male | 358 (53.5) | 65 (33.7) | 58 (39.2) | <0.001 |
| NYHA functional class % I/II/III/IV | 1.6/25.0/58.2/15.1 | 1.0/27.5/63.2/8.3 | 0.7/17.6/70.9/10.8 | 0.027 |
| History of acute PE# | 466 (69.7) | 100 (51.8) | 97 (65.5) | <0.001 |
| Right heart catheterisation at diagnosis | ||||
| MRAP mmHg | 8.0 (5.0–12.0) | 7.0 (4.0–10.0) | 8.0 (5.0–11.8) | <0.001 |
| n (missing) | 640 (29) | 182 (11) | 140 (8) | |
| mPAP mmHg | 45.0 (36.0–51.0) | 42.0 (35.5–51.0) | 40.0 (34.0–52.0) | 0.116 |
| n (missing) | 669 (0) | 193 (0) | 148 (0) | |
| PCWP mmHg | 10.0 (8.0–13.0) | 8.0 (6.0–11.0) | 10.5 (9.0–13.0) | <0.001 |
| n (missing) | 643 (26) | 193 (0) | 148 (0) | |
| Cardiac output L·min−1 | 4.20 (3.40–5.09) | 4.00 (3.15–4.90) | 4.18 (3.33–5.00) | 0.406 |
| n (missing) | 656 (13) | 192 (1) | 144 (4) | |
| CI L·min−1·m−2 | 2.17 (1.80–2.61) | 2.28 (1.86–2.85) | 2.30 (1.86–2.70) | 0.050 |
| n (missing) | 654 (15) | 192 (1) | 141 (7) | |
| PVR dyn·s·cm−5 | 642 (449–901) | 656 (467–912) | 592 (399–962) | 0.544 |
| n (missing) | 642 (27) | 189 (4) | 142 (6) | |
| PVRI dyn·s·cm−5·m2 | 1244 (869–1670) | 1137 (811–1600) | 1085 (740–1749) | 0.172 |
| n (missing) | 631 (38) | 192 (1) | 138 (10) | |
| Numbers operated by PEA or BPA at time of baseline analysis | 593 | 175 | ||
| PVR at the end of ICU¶ dyn·s·cm−5 | 262 (200–351) | 298 (228–394) | 0.004 | |
| n (missing), preliminary data | 507 (86) | 125 (50) | ||
| Reduction in PVR since diagnosis dyn·s·cm−5 | 372 (190–619) | 343 (154–527) | 0.185 | |
| n (missing), preliminary data | 496 (97) | 123 (52) | ||
Values are expressed as median with first and third quartiles (Q1–Q3) or n (%) unless otherwise indicated. PEA: pulmonary endarterectomy; BPA: balloon pulmonary angioplasty; NYHA: New York Heart Association; PE: pulmonary embolism; MRAP: mean right atrial pressure; mPAP: mean pulmonary artery pressure; PCWP: pulmonary capillary wedge pressure; CI: cardiac index; PVR: pulmonary vascular resistance; PVRI: pulmonary vascular resistance index; ICU: intensive care unit. #: unknown cases included in the exploratory analysis of significance. ¶: after last BPA for BPA patients.