TABLE 2

Descriptive analysis of primary and secondary end-points between MasterScreen and HypAir

VariablesMasterScreenHypAirPer cent difference
Primary end-point
DLNO mL·min−1·mmHg−1121.30 (110.13 to 132.48)145.73 (132.04 to 159.41)−16.5 (−17.8 to −15.1)
Secondary end-points
DLCO mL·min−1·mmHg−128.47 (25.81 to 31.13)28.15 (25.46 to 30.84)1.4 (−0.1 to 2.9)
 Alveolar volume L5.80 (5.38 to 6.21)6.28 (5.85 to 6.71)−8.0 (−8.9 to – 7.0)
 Breath-hold time s6.28 (6.17 to 6.39)5.93 (5.81 to 6.05)6.2 (4.6 to 7.8)
 Inspiratory volume L4.66 (4.28 to 5.04)4.68 (4.31 to 5.05)−0.5 (−1.7 to 0.7)
 κNO s−1−6.13 (−6.25 to −6.00)−7.23 (−7.44 to −7.02)−14.6 (−17.3 to −11.9)
 κCO s−1−0.018 (−0.019 to −0.018)−0.022 (−0.022 to −0.021)−15.8 (−17.2 to −14.4)
 KNO mL·min−1·mmHg−1·L−120.8 (19.7 to 21.9)23.1 (21.8 to 24.4)−9.3 (−10.4 to −8.1)
 KCO mL·min−1·mmHg−1·L−14.9 (4.6 to 5.1)4.5 (4.2 to 4.7)10.2 (8.6 to 11.9)
 ΔFANO ppm−38.3 (−38.9 to −37.7)−42.8 (−44.1 to −41.5)−9.4 (−12.8 to −6.0)
 ΔFACO %−0.11 (−0.12 to −0.11)−0.13 (−0.13 to −0.13)−10.9 (−12.4 to −9.4)
 NO, expired/inspired ratio0.117 (0.107 to 0.127)0.100 (0.090 to 0.110)19.2 (13.9 to 24.6)
 O2, expired/inspired ratio0.877 (0.870 to 0.884)0.887 (0.873 to 0.900)−1.4 (−2.7 to −0.01)
 CO, expired/inspired ratio0.470 (0.458 to 0.481)0.475 (0.464 to 0.468)1.3 (−0.2 to 2.8)
 He, expired/inspired ratio0.737 (0.718 to 0.756)0.683 (0.665 to 0.702)−10.1 (−10.9 to −9.3)

Data are presented as mean (95% CI). DLCO: diffusing capacity of the lung for CO; DLNO: diffusing capacity of the lung for NO; κCO: permeability factor for CO; κNO: permeability factor for NO; KNO: transfer coefficient of the lung for NO; KCO: transfer coefficient of the lung for CO; FACO: fractional concentration of CO in the alveolar space; FANO: fractional concentration of NO in the alveolar space; ΔFACO (expired–inspired CO concentration); ΔFANO (expired–inspired NO concentration). Ratios of expired to inspired gas concentrations are also shown.