TABLE 2

The mean of different parameters for chromosomal damage in healthy individuals and lung cancer patients lymphocyte using the cytokinesis block micronucleus assay

Subject	Treatment group	Mean of NDI	Mean of % BiNC	Mean of % MultiNC	Mean per 1000 BiNC cells			Mean of % MNi in MoNC
Subject	Treatment group	Mean of NDI	Mean of % BiNC	Mean of % MultiNC	BiMNi	BiNPB	BiBuds
Healthy volunteers	Untreated lymphocytes	1.92±0.03	60.6±1.6	16.2±1.15	0.4±0.24	0	0	0
	75 μM H₂O₂	1.96±0.03	60.6±0.4	18.4±1.56	12.2±1.11	0.2±0.2	0	6.2±1.59
	0.4 μM MMC	1.88±0.06	59.2±2.4	15.6±3.81	18.0±2.09	0	0	8.4±1.8
	100 U·mL⁻¹ IFN-γ	1.87±0.02	58.8±0.58	14.2±1.2	1.4±0.24	0	0	1.2±0.37
	Blank liposome	1.93±0.04	60.2±1.68	17.0±1.51	0.4±0.24	0	0	0
	IFN-γ liposome	1.98±0.03	61.6±0.4	19.4±1.4	1.2±0.2	0	0	0.6±0.4
	IFN-γ liposome+H₂O₂	1.96±0.02	59.0±2.28	19.8±2.72	4.2±0.86	0	0	3.2±1.28
	IFN-γ+H₂O₂	1.92±0.07	59.6±1.91	17.6±4.45	4.8±0.96	0	0	4.4±1.43
Lung cancer patients	Untreated lymphocytes	1.90±0.03	58.4±2.2	16.4±1.43	7.4±0.6	0.2±0.2	0	3.4±0.4
	75 μM H₂O₂	1.89±0.03	56.0±2.46	17.0±2.07	17.0±1.3	0.6±0.4	0	6.4±1.2
	0.4 μM MMC	1.93±0.02	58.0±2.44	18.0±1.51	20.6±0.81	1.8±0.8	0.2±0.2	9±1.76
	100 U·mL⁻¹ IFN-γ	1.97±0.03	59.6±0.5	19.2±1.59	3.0±0.31	0	0	3±+0
	Blank liposome	1.91±0.02	60.8±0.86	15.2±1.42	5.6±0.4	0.2±0.2	0	3.2±0.48
	IFN-γ liposome	1.87±0.04	57.8±1.24	15.2±2.2	2.2±0.37	0	0	1.8±0.2
	IFN-γ liposome+H₂O₂	1.99±0.03	58.6±2.18	21.0±2.6	6.6±1.2	0	0	4±0.7
	IFN-γ+H₂O₂	1.98±0.03	61.0±1.34	18.6±1.56	8.6±0.92	0	0	5±1.37

NDI: nuclear division index; BiNC: binucleated cells; MultiNC: multinucleated cells; MoNC: mononucleated cells; MMC: Mitomycin C; IFN: interferon.