TABLE 2

Estimated average lifelong healthcare costs (euros) and effectiveness

Base case (i.e. current care)No delayDifference
Screening programme costs-4125-
Hospital costs21 49327 4725979
Medication costs (weighted per treatment group)
 PEA (60%)40 29755 09414 797
 BPA (15%)27 63637 6199983
 PAH-targeted therapy (15%)27 67937 4499770
 No treatment (5%)---
Total lifelong costs117 105161 75944 654
Life expectancy years14.3 17.33.01
QALYs years8.42 10.452.04
Incremental cost-effectiveness ratio14 853 per life-year gained
Incremental cost–utility ratio21 910 per QALY gained

PEA: pulmonary endarterectomy; BPA: balloon pulmonary angioplasty; PH: pulmonary hypertension; QALY: quality-adjusted life-year.