Age- and sex-adjusted endostatin associations with clinical variables in the overall PAH Biobank cohort
| Variable | Regression coefficient |
| RAP mmHg | 1.84 (1.35–2.33, <0.001) |
| mPAP mmHg | 1.99 (0.75–3.23, 0.002) |
| PAWP mmHg | 0.15 (−0.23–0.53, 0.45) |
| PVR Wood units | 0.98 (0.44–1.2, <0.001) |
| Cardiac output L·min−1 | −0.14 (−0.30–0.03, 0.10) |
| Cardiac index L·min−1·m−2 | −0.10 (−0.21–0.01, 0.07) |
| Stroke volume L | −0.005 (−0.008– −0.002, 0.003) |
| Pulmonary arterial compliance mL·mmHg−1 | −0.19 (−0.31– −0.08, 0.001) |
| 6MWD m | −53.5 (−70.7– −36.2, <0.001) |
| NTproBNP pg·mL−1 | 1.12 (1.00–1.25, <0.001) |
Values are presented as β-coefficient (95% confidence interval, p-value) per log endostatin. RAP: right atrial pressure; mPAP: mean pulmonary arterial pressure; PAWP: pulmonary artery wedge pressure; PVR: pulmonary vascular resistance; 6MWD: 6-min walking distance; NTproBNP: N-terminal pro-brain natriuretic peptide.