t0 (baseline) | t1 (8 weeks) | t2 (16 weeks) | Follow-up (28 weeks) | End of study | |
CRQ# | x | x | x | x | |
IPOS¶ | x | x | x | x | |
NRS breathlessness+ | x | x | x | x | |
HADS§ | x | x | x | x | |
EQ-5D-5L, VAS | x | x | x | x | |
SPPBƒ | x | x | x | ||
Lung function | x | x | x | ||
Oxygen saturation | x | x | x | ||
Health service utilisation and medication (FIM-P) | x | x | x | x | |
Patient survival | x | ||||
Adverse events | x | x | x | x | |
Carer Zarit Burden Inventory | x | x | x | ||
Carer EQ-5D-5L, VAS | x | x | x | ||
Carer sleep quality | x | x | x |
t: time; CRQ: Chronic Respiratory Disease Questionnaire; IPOS: Integrated Palliative Care Outcome Scale; NRS: numerical rating scale; HADS: Hospital Anxiety and Depression Scale; VAS: visual analogue scale; SPPB: Short Physical Performance Battery; FIM-P: Questionnaire for Health-Related Resource Use in an Elderly Population. #: total score and subscores (mastery, dyspnoea, fatigue, emotional function), self-administered individualised version; ¶: total score and subscores (somatic symptoms, emotional problems, quality and communication); +: on average in the past 24 h, at rest in the past 24 h, on exertion in the past 24 h; §: depression, anxiety; ƒ: total score and subscores (balance, gait speed, chair stand).