Characteristics of COVID-19 patients on continuous positive airway pressure (CPAP) with pulmonary barotrauma: wave 2

 Patients receiving CPAP, n136
 Barotrauma cases, n9
 Incidence, %6.6
 Age, years, median (range)64 (27–82)
 Male/female, n6/3
 BMI, kg·m−2, median (range)28 (24–36)
 Never-smoker/ex-smoker, n6/3
 Underlying respiratory diagnosis, n
  Pleural plaques1
Baseline characteristics before commencing CPAP
 Respiratory rate, breaths·min−1, median (mean; range)28 (29.5; 20–40)#
PaO2/FIO2 ratio, mmHg, median (mean; range)72 (80.0; 55–122)
CPAP therapy
 Time from commencing CPAP to barotrauma diagnosis, days, median (range)6 (3–10)
 Maximum CPAP pressure received, cmH2O, median (range)12.5 (10–15)
Barotrauma cases
 Bilateral/unilateral pneumothorax, n4/1
 Requirement of intercostal chest drain insertion, n3
 Pneumomediastinum, n9
 Surgical emphysema (radiological diagnosis), n8
 Outcome, n

COVID-19: coronavirus disease 2019; BMI: body mass index; PaO2: arterial oxygen tension; FIO2: inspiratory oxygen fraction. #: data available for eight out of nine patients.