Coagulation factor levels in patients with stable COPD and control subjects
| Coagulation factor levels | Control group | COPD | p-value# |
| Subjects n | 42 | 103 | |
| Fibrinogen mg·dL−1 | 346±65 | 399±82 | <0.001 |
| FII % | 109±19 | 122±22 | 0.004 |
| FV % | 112±19 | 131±25 | 0.015 |
| FVII % | 108±19 | 115±23 | 0.113 |
| FVIII % | 122±20 | 143±32 | <0.001 |
| FIX % | 111 (106–123) | 116 (108–126) | 0.126 |
| FX % | 98 (88–107) | 111 (94–134) | 0.002 |
| D-dimers ng·mL−1 | 240 (180–400) | 360 (230–600) | 0.001 |
| INR | 1.01 (0.95–1.05) | 1.00 (0.93–1.05) | 0.853 |
| PT s | 14.1 (13.1–14.5) | 13.7 (12.8–14.4) | 0.184 |
| aPTT s | 29.8±3.0 | 28.2±3.4 | 0.515 |
| Free protein S antigen % | 116 (98–121) | 95 (85–105) | <0.001 |
| Protein C % | 116.2±17.1 | 112.6±18.1 | 0.150 |
| Antithrombin % | 102.3±13.2 | 94.4±11.5 | 0.001 |
n=145. All values are presented as mean±sd or median (interquartile range). sd: standard deviation; PT: prothrombin time; aPTT: activated partial thromboplastin time. #: Mann–Whitney U-test.