Healthy_{Symp} (n=126) | Smokers_{Asym} (n=159) | Smokers_{Symp} (n=115) | Asthma (n=122) | COPD (n=46) | |

ΔX_{rs6} (abs) | 0.012* | 0.001* | 0.108 | 0.678 | 0.077 |

ΔX_{rs6} (Z-score) | 0.039 | 0.035 | 0.078 | 0.648 | 0.774 |

ΔX_{rs6,insp} (abs) | 0.012* | 0.035 | 0.023* | 0.824 | 0.549 |

ΔEFLi (abs) | 0.003* | 0.0003* | 0.043 | 0.556 | 0.118 |

Asym: asymptomatic; abs: absolute; insp: inspiratory; EFLi: expiratory flow limitation index. Comparisons were by McNemar tests. *: significant p-values after Benjamini–Hochberg adjustment for multiple comparisons, using α=0.10 (10% false discovery rate).