TABLE 4

Independent predictors for connective tissue disease (CTD) diagnosis in interstitial lung disease (ILD) identified by exploratory multivariable regression

	Predictors^#	Adjusted OR^¶	95% CI	p-value
A) Including CTD manifestations	Any CTD manifestation	62.84	13.93–283.40	<0.001
	Microhaemorrhages	13.45	2.14–84.32	0.006
B) Excluding CTD manifestations	Positive ENA	11.59	1.80–74.55	0.010
	Microhaemorrhages	22.54	1.89–269.05	0.014
	Low capillary density	5.66	1.32–24.20	0.019

A) Independent predictors for CTD diagnosis in ILD respective to retained nailfold characteristics, clinical, serological and radiological variables. B) Independent predictors for CTD diagnosis in ILD excluding CTD manifestations, respective to remaining nailfold characteristics, serological and radiological variables. ENA: extractable nuclear antibodies. ^#: all retained variables in initial multivariable regression shown in supplementary table S8; ^¶: adjusted for age, sex, smoking, FVC%, treatment and pulmonary hypertension.