Descriptive statistics of the secondary outcomes of the intervention
| T1 | T2 | T3 | ||||
| Intervention | Placebo | Intervention | Placebo | Intervention | Placebo | |
| Physical capacity and activity | ||||||
| 6MWD (m) | 456.5±94.1 | 459.0±74.7 | 463.9±88.0 | 452.9±76.3 | 454.4±108.0 | 448.2±86.8 |
| 6MWD (% predicted) | 73.6±13.9 | 72.5±10.9 | 74.9±13.8 | 71.9±12.5 | 73.2±16.7 | 71.3±15.2 |
| SPPB total score (0–12) | 10.0 (9.0–11.0) | 11.0 (9.0–12.0) | 10.0 (9.0–11.0) | 10.0 (9.0–11.0) | 11.0 (10.0–12.0) | 10.0 (9.0–11.0) |
| Sedentary time (h·day−1) | 18.1±1.9 | 18.4±1.7 | 18.3±1.8 | 18.5±1.8 | 18.3±1.6 | 18.2±1.7 |
| Standing time (h·day−1) | 4.2 (2.8–5.3) | 3.8 (3.0–5.1) | 4.0 (3.0–5.2) | 3.7 (3.4–4.6) | 3.7 (3.2–5.2) | 4.0 (3.4–5.2) |
| Stepping time (h·day−1) | 1.8 (1.1–2.2) | 1.6 (1.0–1.8) | 1.7 (1.1–2.1) | 1.3 (0.9–1.9) | 1.5 (1.2–2.2) | 1.5 (1.1–1.9) |
| Sedentary breaks (number·day−1) | 31.7 (26.1–40.9) | 31.5 (25.4–39.6) | 36.4 (27.6–40.1) | 34.7 (30.1–38.3) | 37.1 (29.0–39.7) | 35.1 (27.9–38.6) |
| Sedentary bouts (>30 min) (number·day−1) | 35±12 | 31±13 | 38±12 | 32±15 | 34±14 | 33±11 |
| High-intensity PA | 8.73 (4.09–20.21) | 7.74 (4.08–17.86) | 8.68 (2.29–26.58) | 9.36 (4.29–16.07) | 9.13 (3.42–15.64) | 8.62 (2.75–15.31) |
| Dietary quality | ||||||
| AHEI-2010 | 50.0±12.8 | 50.0±9.6 | 53.7±13.3 | 55.9±8.7 | 51.0±13.5 | 52.1±12.4 |
| Cognitive stress susceptibility and perception | ||||||
| AUC (CAR) (arbitrary units) | 534 (270–609) | 512 (341–690) | 459 (264–759) | 424 (342–630) | — | — |
| Delta (SECPT) (μmol·L−1) | 0.00 (0.00–1.66) | 0.00 (0.00–2.68) | 0.00 (0.00–0.06) | 0.00 (0.00–0.58) | 0.00 (0.00–2.04) | 0.00 (0.00–0.72) |
| Perceived Stress Scale | 10.9±5.3 | 13.3±6.9 | 11.7±4.8 | 13.4±5.8 | 10.3±5.5 | 13.3±6.7 |
| Healthy lifestyle goal recall | ||||||
| Content recall (0–4) | — | — | 0.3 (0.0–1.0) | 0.3 (0.0–0.5) | 0.0 (0.0–0.6) | 0.0 (0.0–0.4) |
| Procedure recall (0–2) | — | — | 1.0 (0.0–2.0) | 0.0 (0.0–1.3) | 0.0 (0.0–2.0) | 0.0 (0.0–2.0) |
All data expressed as mean±SD or median (inter-quartile range) depending on the normality of the distribution of the data. 6MWD: 6-min walk distance; SPPB: Short Physical Performance Battery; PA: physical activity; AHEI: Alternative Healthy Eating Index; AUC: area under the curve; CAR: cortisol awakening response; SECPT: socially evaluated cold pressor test; —: not taken at this time point.