Bronchodilator responses in steroid-naïve asthma patients with pre-bronchodilator (pre-BD) forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) <0.7 versus FEV1/FVC ≥0.7 (N=219)
| pre-BD FEV1/FVC ≥0.7 (n=151) | pre-BD FEV1/FVC <0.7 (n=68) | p-value | |
| ΔFEV1, mL | 210 (110–370) | 285 (180–478) | 0.002 |
| ΔFVC, mL | 110 (20–240) | 200 (90–320) | 0.012 |
| ΔFEV1, % of the initial FEV1 | 7.3 (3.8–12.5) | 13.5 (9.3–19.4) | <0.001 |
| ΔFVC % of the initial FVC | 3.0 (0.5–6.6) | 6.4 (2.2–8.5) | 0.008 |
| ΔFEV1, % of the predicted FEV1 | 6.0 (3.2–9.8) | 8.9 (5.8–13.2) | 0.001 |
Data are presented as the median (interquartile range). Spirometry showing the highest reversibility chosen from each patient.