TABLE 3

Multivariable odds ratios for factors at the diagnostic visit associated with the fulfilment of thresholds of change in forced expiratory value in 1 s (ΔFEV1)  >9% of predicted FEV1 and ΔFEV1 ≥12% and 200 mL of the initial FEV1

ΔFEV1≥9% of predicted FEV1p-valueΔFEV1≥12% of the initial FEV1+200 mLp-value
Age ≥45 years1.54 (0.73–3.22)0.2581.72 (0.77–3.85)0.190
Male0.71 (0.33–1.50)0.3650.43 (0.19–1.00)0.050
Symptoms, AQ201.10 (0.97–1.14)0.2281.02 (0.94–1.11)0.630
Total IgE <100 kU·L−12.06 (0.97–4.37)0.0602.84 (1.24–6.51)0.014
Blood eosinophils >0.25×109 per L1.90 (0.89–4.10)0.0972.55 (1.10–5.88)0.029
Post-bronchodilator FEV1/FVC<0.7 and ≥10 pack-years0.26 (0.60–1.11)0.6900.39 (0.11–1.43)0.155
Pre-bronchodilator FEV1 <80% predicted#6.03 (2.11–17.21)<0.00115.93 (5.00–50.80)<0.001
Pre-bronchodilator FVC >90% predicted#4.71 (1.68–13.18)0.0032.90 (0.99–8.53)0.053

Ig: immunoglobulin; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; AQ20: Airways Questionnaire 20. #: Measured from the spirometry with highest reversibility. Data are presented as ORs (95% CIs). BMI and smoking were not significantly associated with the thresholds and were excluded from the model. Statistically significant associations are presented in bold.