TABLE 1

Baseline characteristics of the patients included in the study

Patients36
Age, years27 (22–31)
Male/female (ratio)23/13 (1.8)
BMI, kg·m−221.5 (19.6–24.1)
Smoker or ex-smoker7 (20)
Ethnicity
 Sub-Saharan Africa27 (75)
 Caribbean6 (17)
 Other3 (8)
Sickle-cell disease characteristics
 Genotype
  SS34 (94)
  SC1 (3)
  S β-thalassaemia1 (3)
 Baseline haemoglobin, g·dL−18.8 (8.0–9.5)
 History of acute complications
  Vaso-occlusive crisis36 (100)
  Acute chest syndrome31 (86)
 Healthcare consumption in the preceding year
  Emergency room2 (1–5)
  Hospitalisation in conventional ward2 (1–4)
  Hospitalisation in ICU0 (0–1)
 Chronic complications
  Proteinuria9 (25)
  Chronic renal insufficiency0 (0)
  Retinopathy18 (50)
  Biliary lithiasis23 (64)
  Cholecystectomy20 (56)
  Splenectomy3 (8)
  Bone complications#13 (36)
  Leg ulcers1 (3)
 Chronic treatments
  Hydroxyurea24 (67)
  Chronic exchange transfusions0 (0)

Data are presented as n, median (interquartile range) or n (%). BMI: body mass index; ICU: intensive care unit. #: osteonecrosis, arthrosis and osteomyelitis.