Characteristics of nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (N-ERD), asthma, rhinitis and NSAID-induced dyspnoea without N-ERD
| N-ERD | Asthma without N-ERD | Rhinitis without asthma or N-ERD | NSAID-induced dyspnoea without N-ERD | p-value | |
| Patients | 110 | 818 | 3168 | 22 | |
| Age years | 52±14 | 46±15* | 46±14* | 53±16 | <0.001 |
| Female | 72 (65.5) | 460 (56.2) | 1767 (55.8) | 16 (72.7) | 0.090 |
| BMI kg·m−2 | 27.3±5.7 | 26.7±5.2 | 26.1±7.4 | 26.6±15.5 | 0.049 |
| Age at asthma diagnosis years | 32±17 | 25±18* | NA | NA | 0.021 |
| Asthma diagnosis | |||||
| <12 years | 10 (16.4) | 235 (30.1) | NA | NA | 0.027 |
| 12–39 years | 24 (39.3) | 334 (42.8) | |||
| ≥40 years | 27 (44.3) | 212 (27.1) | |||
| Physician-diagnosed allergic rhinitis | 48 (43.6) | 471 (57.6)* | 1264 (39.6) | 0 (0.0)* | <0.001 |
| Physician-diagnosed COPD | 17 (15.5) | 67 (8.2) | 68 (2.1)* | 0 (0.0) | <0.001 |
| Family history of asthma | 53 (48.2) | 355 (43.4) | 823 (26.0)* | 5 (22.7) | <0.001 |
| Never-smoker | 49 (44.5) | 383 (47.2)* | 1689 (53.3) | 6 (27.3) | <0.001 |
| Current smoker | 24 (21.8) | 192 (23.5) | 724 (22.9) | 10 (45.5) | |
| Ex-smoker | 37 (33.6) | 240 (29.3)* | 755 (23.8) | 6 (27.3) | |
| Occupational exposure to VGDF | 48 (45.7) | 308 (38.8) | 1064 (34.2) | 5 (23.8) | 0.007 |
| Childhood exposure to farming environment | 43 (39.8) | 210 (26.2)* | 702 (22.4)* | 5 (29.4) | <0.001 |
Data are presented as n, mean±sd or n (%), unless otherwise stated. Missing data in the N-ERD group: body mass index (BMI) n=2, occupational exposure to vapours, gases, dusts and fumes (VGDF) n=3, childhood exposure to farming environment n=2. ANOVA was used for continuous variables with Tukey's post hoc test to determine statistically significant differences and multigroup comparisons. Pearson's Chi-squared test with the z-test was used for categorical variables. NA: not applicable. *: p<0.05 versus N-ERD group.