TABLE 1

Comparison of the analytical subsample (n=434) with the whole Isle of Wight birth cohort (IOWBC) (n=1261) on ages of pubertal events and lung function

Variables	Cohort samples	Subsamples	p-value
Subjects n	1261	434
Age of pubertal events years
Female
Breast growth	12.43±1.58	12.29±1.60	0.20
Body hair growth	12.25±1.43	12.21±1.42	0.66
Growth spurt	12.52±1.70	12.36±1.80	0.21
Skin changes	13.11±1.50	13.08±1.59	0.79
Menarche	12.72±1.42	12.60±1.37	0.18
Male
Body hair growth	13.41±1.37	13.26±1.40	0.14
Growth spurt	13.72±1.67	13.54±1.63	0.14
Voice deepening	14.24±1.24	14.07±1.19	0.05
Facial hair growth	15.38±1.16	15.32±1.09	0.45
Skin changes	13.99±1.38	13.94±1.29	0.61
Lung function L (age 26 years)
Female
FVC	4.24±0.54	4.29±0.55	0.24
FEV₁	3.42±0.43	3.45±0.42	0.45
Male
FVC	5.85±0.82	5.88±0.82	0.89
FEV₁	4.61±0.72	4.66±0.72	0.50

Data presented as mean±sd. FVC: forced vital capacity; FEV₁: forced expiratory volume in 1 s.