TABLE 1

Baseline characteristics of patients with stable fibrosing interstitial lung disease (ILD)

PatientsHealthy controls
Subjects, n11938
Age years70±952±11
Sex (male), n (%)69 (58)16 (42)
Smoking history (yes), n (%)73 (61)11 (29)
Diagnosis of fibrosing ILD, n
 IPF78
 NSIP11
 Unclassifiable ILD10
 PPFE8
 CTD-ILD12
Treatment at the time of analysis, n
 Corticosteroids25
 Pirfenidone19
 Nintedanib15
Laboratory data
 LDH U· L−1252±54
 KL-6 U m·L−11029±680
 SP-D ng· mL−1215±148
Pulmonary function
 FVC mL2133±743
 %FVC75.9±20.4
DLCO %59.8±20.9

Data are presented as mean±sd, unless otherwise stated. IPF: idiopathic pulmonary fibrosis; NSIP: nonspecific interstitial pneumonia; CTD-ILD: connective tissue disease-associated ILD; PPFE: pleuroparenchymal fibroelastosis; LDH: lactate dehydrogenase; SP-D: surfactant protein-D; KL-6: Krebs von den Lungen-6; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide.