TABLE 2

Demographics of patients undergoing bronchoalveolar lavage for suspicion of pulmonary infection

Patient characteristicsn (%), mean±sdMultiplex PCRConventional culturep-value
Age years62±15.560±15.960±14.60.82
Female198/470 (42)140/322 (43)58/148 (39)0.42
Weight kg68±17.9670±18.169±17.70.83
Height cm169±9.4169±9.6169±9.00.82
Setting0.78
 Ambulatory213/605 (35)147/417 (35)64/188 (34)
 Hospitalised392/605 (65)270/417 (65)124/188 (66)
Smoking status0.79
 Current smokers126/605 (21)86/403 (21)40/183 (22)
 Former smokers237/605 (39)160/403 (40)77/183 (42)
 Pack-years, median (IQR)30 (15–50)30 (15–50)30 (18.75–50)0.78
Respiratory symptoms before bronchoscopy:
 Cough316/399(79)215/370 (58)101/167 (60)0.64
 Sputum239/537(45)167/370 (45)72/167 (43)0.71
 Dyspnoea226/399(57)156/370 (42)70/167 (42)1.00
 Thoracic pain66/399(17)50/370 (14)16/167 (10)0.26
Pathological findings on CT and/or radiograph284/348 (82)194/235 (83)90/113 (80)0.56
 Consolidation223 (79)154 (79)69 (77)0.47
 Pleural effusion101 (36)76 (39)25 (28)0.06
 Interstitial pattern63 (22)40 (21)23 (26)0.46
 Cavities13 (5)10 (5)3 (3)0.56
Laboratory findings values before bronchoscopy
 C-reactive protein mg·L−120±8768±9351±700.27
 Procalcitonin ng mL−10.08±1.220.4±1.40.2±0.60.37
 White blood cells (×109)7.94±5.89.0±5.98.6±5.50.45
 Neutrophil leukocyte count (×109)5.28±4.66.5±4.96.1±3.70.95
 Haemoglobin g·L−1120±24118±24120±230.46
 Glucose mmol·L−15.9±2.56.5±2.27.0±3.00.18
 BUN mmol·L−16.3±5.447.8±5.67.8±5.20.46
 Creatinine μmol L−176±6394±6298±680.24
Final diagnosis
 Bacterial infection18854/144 (37.5)45/188 (24)0.00
 Probably bacterial infection18321/116 (18)16/183 (9)
 No bacterial infection23432/160 (20)22/234 (9)

IQR: interquartile range; CT: computed tomography; BUN: blood urea nitrogen.