Baseline characteristics of participants

Age (years)57.6±13.3
Female (%)48.8
BMI (kg·m−2)31.3±7.3
Smoking (pack-years)6.8±11.6
SABA (puffs·day−1)10 (14)
LABA (%)100
LAMA (%)100
Inhaled steroid (beclomethasone µg·day−1)1730±941
Daily oral steroid (%)62.7
Prednisolone dose (mg·day−1)7 (15)
Monoclonal antibodies (%)67.4
Exacerbations (per annum)4 (8)
Pre-bronchodilator FEV1 (% predicted)49.1±15.8
Forced expiratory ratio (%)50.4±11.3
Bronchodilator response FEV1 (%)15.1±14.5
RV (% predicted)150.3±40.8
TLC (% predicted)104.7±17.4
RV/TLC (%)51.3±10.5
KCO (% predicted)94.0±23.3
Blood eosinophil count (cells·µL−1)190±210
Serum IgE (IU·mL−1)588±2324

Data are presented as n, mean±sd or median (interquartile range), unless otherwise stated. BMI: body mass index; SABA: short-acting β-agonist; LABA: long-acting β-agonist; LAMA: long-acting muscarinic antagonist; ACQ: Asthma Control Questionnaire; FEV1: forced expiratory volume in 1 s; RV: residual volume; TLC: total lung capacity; KCO: diffusing capacity of the lung for carbon monoxide corrected for alveolar volume.