Response to bronchial thermoplasty at 12 months post procedure
Baseline | 12 months post bronchial thermoplasty | p-value | |
Symptom score (ACQ) | 3.3±1.0 | 2.0±1.3 | 0.001 |
SABA (puffs·day−1) | 10 (14) | 2 (6) | 0.001 |
Prednisolone dose (mg·day−1) | 7 (15) | 0 (10) | 0.001 |
Exacerbations (per annum) | 4 (8) | 1 (3) | 0.001 |
FEV1 (L) | 1.43±0.63 | 1.51±0.70 | 0.140 |
FEV1 (% pred) | 49.1±15.8 | 52.7±18.1 | 0.035 |
Vital capacity (L) | 2.91±0.94 | 3.01±1.00 | 0.078 |
TLC (L) | 6.01±1.43 | 5.95±1.42 | 0.338 |
TLC (% pred) | 104.7±17.4 | 103.9±20.6 | 0.567 |
RV (L) | 3.09±0.95 | 2.93±0.94 | 0.026 |
RV (% pred) | 150.3±40.8 | 141.8±46.0 | 0.023 |
RV/TLC (%) | 51.3±10.5 | 49.3±10.8 | 0.009 |
Data are presented as mean±sd or median (interquartile range), unless otherwise stated. Bold type represents statistical significance. n=43. ACQ: Asthma Control Questionnaire; SABA: short-acting β-agonist; FEV1: forced expiratory volume in 1 s; TLC: total lung capacity; RV: residual volume.