TABLE 4

Baseline comparisons: nonresponders versus responders using change in Asthma Control Questionnaire score (ΔACQ)

Nonresponders (ΔACQ <0.5)Responders (ΔACQ ≥0.5)p-value
Patients1627
ΔACQ at 12 months−0.03±0.5−2.2±0.9
Baseline characteristics
 Age (years)56.4±13.257.3±13.60.872
 Male/female8/814/130.910
 BMI (kg·m−2)30.2±7.532.4±7.50.22
 Smoking history (pack-years)0 (0)1 (14)0.040
 ACQ3.1±0.83.5±1.00.199
 SABA (puffs·day−1)8.5 (14)10 (13)0.604
 Prednisolone dose (mg·day−1)8.8 (15)5 (15)0.476
 Exacerbations (per annum)4 (7)4 (7)0.395
 FEV1 (% pred)47.2±10.950.3±18.10.534
 TLC (% pred)100±13107±200.200
 RV (% pred)146±33153±450.601
 RV/TLC (%)53±1051±110.571

Data are presented as n, mean±sd or median (interquartile range), unless otherwise stated. BMI: body mass index; SABA: short-acting β-agonist; FEV1: forced expiratory volume in 1 s; TLC: total lung capacity; RV: residual volume.