Baseline comparisons: nonresponders versus responders using change in Asthma Control Questionnaire score (ΔACQ)
Nonresponders (ΔACQ <0.5) | Responders (ΔACQ ≥0.5) | p-value | |
Patients | 16 | 27 | |
ΔACQ at 12 months | −0.03±0.5 | −2.2±0.9 | |
Baseline characteristics | |||
Age (years) | 56.4±13.2 | 57.3±13.6 | 0.872 |
Male/female | 8/8 | 14/13 | 0.910 |
BMI (kg·m−2) | 30.2±7.5 | 32.4±7.5 | 0.22 |
Smoking history (pack-years) | 0 (0) | 1 (14) | 0.040 |
ACQ | 3.1±0.8 | 3.5±1.0 | 0.199 |
SABA (puffs·day−1) | 8.5 (14) | 10 (13) | 0.604 |
Prednisolone dose (mg·day−1) | 8.8 (15) | 5 (15) | 0.476 |
Exacerbations (per annum) | 4 (7) | 4 (7) | 0.395 |
FEV1 (% pred) | 47.2±10.9 | 50.3±18.1 | 0.534 |
TLC (% pred) | 100±13 | 107±20 | 0.200 |
RV (% pred) | 146±33 | 153±45 | 0.601 |
RV/TLC (%) | 53±10 | 51±11 | 0.571 |
Data are presented as n, mean±sd or median (interquartile range), unless otherwise stated. BMI: body mass index; SABA: short-acting β-agonist; FEV1: forced expiratory volume in 1 s; TLC: total lung capacity; RV: residual volume.