Primary and secondary multivariate analyses
Outcome | Events/person-months | Events/person-months | Multivariate IRR (95% CI) |
Serious adverse events | Standard treatment with bedaquiline# | Prolonged treatment with bedaquiline | |
Up to 5 months after bedaquiline cessation | 38/767 | 18/405 | 0.82 (0.42–1.61) |
Within the first 190 days of treatment | 33/410 | 10/187 | 0.73 (0.33–1.61) |
Serious adverse events | Within the first 190 days of treatment | From day 190 until 5 months after bedaquiline cessation | |
Among persons receiving prolonged treatment | 10/187 | 8/212 | 0.75 (0.30–1.88) |
#: reference group.