Parameter | Sensitivity | Specificity | PPV | False-positive rate | Positive LR | NPV | False-negative rate | Negative LR | Number-needed-to-catheterise |
Peak load <80% predicted | 28/34 (0.82) | 25/54 (0.46) | 28/57 (0.49) | 29/57 (0.51) | 1.53 | 25/31 (0.81) | 6/31 (0.19) | 0.38 | 57/88 (0.65) |
Peak V′O2 <80% predicted | 29/34 (0.85) | 26/54 (0.48) | 29/57 (0.51) | 28/57 (0.49) | 1.64 | 26/31 (0.84) | 5/31 (0.16) | 0.31 | 57/88 (0.65) |
V′O2/WR <8.4 mL·min−1·W−1 | 23/31 (0.74) | 42/51 (0.82) | 23/32 (0.72) | 9/32 (0.28) | 4.20 | 42/50 (0.84) | 8/50 (0.16) | 0.31 | 32/82 (0.39) |
O2 pulse <80% predicted | 17/34 (0.50) | 41/54 (0.76) | 17/30 (0.57) | 13/30 (0.43) | 2.08 | 41/58 (0.71) | 17/58 (0.29) | 0.66 | 30/88 (0.34) |
PETCO2 peak exercise <4.0 kPa | 22/34 (0.65) | 32/54 (0.59) | 22/44 (0.50) | 22/44 (0.50) | 1.59 | 32/44 (0.73) | 12/44 (0.27) | 0.60 | 44/88 (0.50) |
V′E/V′CO2 AT ≥34 | 22/32 (0.69) | 37/54 (0.69) | 22/39 (0.56) | 17/39 (0.44) | 2.18 | 37/47 (0.79) | 10/47 (0.21) | 0.46 | 39/86 (0.45) |
AT: anaerobic threshold; CPET: cardiopulmonary exercise testing; LR: likelihood ratio; NPV: negative predictive value; PETCO2: end-tidal carbon dioxide partial pressure; PH: pulmonary hypertension; PPV: positive predictive value; V′E/V′CO2: ventilatory equivalent for carbon dioxide; V′O2: oxygen consumption; WR: work rate.