Exposure | Male never asthma | Male childhood asthma in remission | p-value | Male adolescent onset asthma | p-value | Male persistent asthma | p-value | Female never asthma | Female childhood asthma in remission | p-value | Female adolescent onset asthma | p-value | Female persistent asthma | p-value |
Subjects n | 569 | 169 | 66 | 73 | 797 | 150 | 142 | 89 | ||||||
Mother asthma | 42 (8.4) | 37 (22) | <0.001 | 13 (20) | 0.003 | 13 (18) | 0.010 | 52 (7.1) | 20 (13) | 0.011 | 24 (17) | <0.001 | 24 (27) | <0.001 |
Father asthma | 38 (7.6) | 21 (23) | 0.053 | 7 (11) | 0.40 | 7 (9.6) | 0.56 | 52 (7.1) | 21 (14) | 0.004 | 13 (9.5) | 0.33 | 20 (23) | <0.001 |
Early wheeze | 20 (4.2) | 86 (52) | <0.001 | 5 (8.1) | 0.17 | 32 (45) | <0.001 | 17 (2.4) | 68 (17) | <0.001 | 4 (3.0) | 0.72 | 34 (40) | <0.001 |
RSV <19 months | 9 (1.8) | 17 (10) | <0.001 | 2 (3.1) | 0.49 | 6 (8.3) | 0.001 | 21 (3.0) | 18 (12) | <0.001 | 6 (4.4) | 0.38 | 8 (9.1) | 0.004 |
Maternal smoking during pregnancy | 48 (9.7) | 23 (14) | 0.16 | 5 (7.6) | 0.57 | 10 (14) | 0.30 | 84 (11) | 24 (16) | 0.31 | 13 (9.2) | 0.21 | 14 (16) | 0.43 |
Secondary smoke exposure | 246 (49) | 86 (51) | 0.66 | 33 (50) | 0.87 | 42 (58) | 0.17 | 394 (54) | 93 (62) | 0.057 | 76 (54) | 1.0 | 60 (67) | 0.013 |
Daily smoking at 24 years | 29 (5.8) | 8 (4.8) | 0.61 | 4 (6.1) | 0.93 | 5 (6.9) | 0.72 | 58 (7.9) | 15 (10) | 0.39 | 15 (11) | 0.29 | 8 (9.0) | 0.72 |
Living on a busy road at age 24 years | 121 (24) | 38 (23) | 0.71 | 17 (26) | 0.76 | 21 (29) | 0.43 | 148 (20) | 45 (30) | 0.009 | 31 (22) | 0.65 | 26 (30) | 0.049 |
Allergic sensitisation at 4 and/or 8 years | 97 (23) | 50 (32) | 0.036 | 25 (45) | <0.001 | 47 (67) | <0.001 | 92 (15) | 30 (23) | 0.028 | 45 (41) | <0.001 | 40 (51) | <0.001 |
High BMI at 8 years of age | 74 (20) | 25 (17) | 0.57 | 10 (20) | 0.94 | 15 (24) | 0.40 | 94 (18) | 22 (19) | 0.63 | 27 (26) | 0.035 | 23 (33) | 0.002 |
High BMI at 24 years | 128 (25) | 44 (26) | 0.88 | 17 (26) | 0.96 | 27 (37) | 0.038 | 131 (18) | 31 (21) | 0.41 | 37 (26) | 0.022 | 26 (29) | 0.010 |
Data presented as n (%) unless indicated otherwise. Significant results in bold. High BMI: body mass index defined as overweight/obese for the age group; RSV: respiratory syncytial virus infection up to 19 months of age.