Characteristics of the training and testing datasets

Training datasetTesting dataset
Observations n19482
Female118 (61)58 (71)
 PAH117 (60)50 (61)
 PH due to left heart disease1 (1)
 PH due to lung disease4 (2)1 (1)
 CTEPH64 (33)28 (34)
 Miscellaneous8 (4)3 (4)
Haemodynamics at baseline
 mPAP, mmHg42±4.139±13.0
 PVR, mmHg12±636±4
 PAWP, mmHg11±411±4
 CI, mL/min/kg2.8±0.82.9±0.7
 Age, years59±1458±15
 Height, cm169±11169±10
 Weight, cm76±1973±17
 BMI, kg/m227±525±5
 NYHA functional class2.2±0.72.2±0.6
6-min walk test
 6-min walk distance, m504±85503±90
 At rest
  Systolic BP, mmHg125±18120±14
  Diastolic BP, mmHg79±1278±12
  Heart rate, bpm84±1484±12
  Peripheral oxygen saturation, %96±396±3
 At peak exercise
  Systolic BP, mmHg145±25142±26
  Diastolic BP, mmHg83±1482±13
  Heart rate, bpm121±21121±22
  Heart rate response, bpm37±1937±20
  Peripheral oxygen saturation, %89±9.090±7.8
  BORG CR10, score4.7±24.6±2
Cardiopulmonary exercise test
VO2max, mL/min/kg15.3±3.816.1±3.7
 Maximal workload, Watts93±3396±36

Data are presented as n (%) or mean±sd, unless otherwise stated. BMI: body mass index; BP: blood pressure; CI: cardiac index; CTEPH: chronic thromboembolic pulmonary hypertension; mPAP: mean pulmonary arterial pressure; NYHA: New York Heart Association; PAH: pulmonary arterial hypertension; PAWP: pulmonary arterial wedge pressure; PH: pulmonary hypertension; PVR: pulmonary vascular resistance; VO2max: maximal oxygen uptake.