Characteristics of the training and testing datasets
| Training dataset | Testing dataset | |
| Observations n | 194 | 82 |
| Female | 118 (61) | 58 (71) |
| Diagnosis | ||
| PAH | 117 (60) | 50 (61) |
| PH due to left heart disease | 1 (1) | |
| PH due to lung disease | 4 (2) | 1 (1) |
| CTEPH | 64 (33) | 28 (34) |
| Miscellaneous | 8 (4) | 3 (4) |
| Haemodynamics at baseline | ||
| mPAP, mmHg | 42±4.1 | 39±13.0 |
| PVR, mmHg | 12±63 | 6±4 |
| PAWP, mmHg | 11±4 | 11±4 |
| CI, mL/min/kg | 2.8±0.8 | 2.9±0.7 |
| Characteristics | ||
| Age, years | 59±14 | 58±15 |
| Height, cm | 169±11 | 169±10 |
| Weight, cm | 76±19 | 73±17 |
| BMI, kg/m2 | 27±5 | 25±5 |
| NYHA functional class | 2.2±0.7 | 2.2±0.6 |
| 6-min walk test | ||
| 6-min walk distance, m | 504±85 | 503±90 |
| At rest | ||
| Systolic BP, mmHg | 125±18 | 120±14 |
| Diastolic BP, mmHg | 79±12 | 78±12 |
| Heart rate, bpm | 84±14 | 84±12 |
| Peripheral oxygen saturation, % | 96±3 | 96±3 |
| At peak exercise | ||
| Systolic BP, mmHg | 145±25 | 142±26 |
| Diastolic BP, mmHg | 83±14 | 82±13 |
| Heart rate, bpm | 121±21 | 121±22 |
| Heart rate response, bpm | 37±19 | 37±20 |
| Peripheral oxygen saturation, % | 89±9.0 | 90±7.8 |
| BORG CR10, score | 4.7±2 | 4.6±2 |
| Cardiopulmonary exercise test | ||
| V′O2max, mL/min/kg | 15.3±3.8 | 16.1±3.7 |
| Maximal workload, Watts | 93±33 | 96±36 |
Data are presented as n (%) or mean±sd, unless otherwise stated. BMI: body mass index; BP: blood pressure; CI: cardiac index; CTEPH: chronic thromboembolic pulmonary hypertension; mPAP: mean pulmonary arterial pressure; NYHA: New York Heart Association; PAH: pulmonary arterial hypertension; PAWP: pulmonary arterial wedge pressure; PH: pulmonary hypertension; PVR: pulmonary vascular resistance; V′O2max: maximal oxygen uptake.