Implementation metric | Outcome | ||||||
FVC (p-value) | DLCO (p-value) | EQ-Health Index (p-value) | K-BILD breathlessness (p-value) | K-BILD psychological (p-value) | K-BILD symptoms (p-value) | K-BILD total (p-value) | |
Proportion of prescribed drug taken (taking adherence) | 0.126 (0.53) | 0.161 (0.53) | −0.073 (0.77) | 25.1 (0.30) | 31.6 (0.21) | 44.9 (0.13) | 17.7 (0.24) |
Proportion of days with the correct number of doses taken (correct dosing) | 0.304 (0.03#) | 0.223 (0.22) | 0.106 (0.59) | 33.2 (0.09) | 7.89 (0.66) | 27.5 (0.20) | 17.1 (0.13) |
Proportion of too short dosing intervals | −1.621 (0.00#) | −1.531 (0.01#) | −0.596 (0.28) | −73.5 (0.11) | 16.3 (0.70) | −97.2 (0.05) | −28.8 (0.29) |
Proportion of drug holidays | −0.626 (0.87) | −0.903 (0.85) | 1.329 (0.79) | 71.8 (0.86) | 108 (0.78) | 305 (0.50) | 54.8 (0.82) |
The table contains the slopes of the random intercept models linking implementation to outcomes. The slopes are dimensionless. FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; K-BILD: The King's Brief Interstitial Lung Disease questionnaire. #: significance at the 0.05 level.